Document Detail

Computational methods for protein sequence analysis.
MedLine Citation:
PMID:  18429149     Owner:  NLM     Status:  MEDLINE    
This unit is presented as a guide to addressing the issue of what to do with a protein sequence once it is obtained. A theoretical background for protein sequence analysis is provided first, followed by a discussion of matrix methods for sequence comparison (Matrix Methods for Sequence Comparison: Dot Plots). Sequence similarity searching is then presented, including the BLAST and FASTA databases. Other aspects of protein sequence analysis covered here are alignment methods, scoring matrices, multiple alignments, cluster methods and trees, and identification of functional sites.
G Michaels; R Garian
Related Documents :
24277689 - The complex evolutionary dynamics of hsp70s: a genomic and functional perspective.
20046539 - Finding occurrences of relevant functional elements in genomic signatures.
9501499 - Phylogenetic profiles: a graphical method for detecting genetic recombinations in homol...
19494099 - Causes of injuries resulting in hospitalisation in australia: assessing coder agreement...
24071059 - Complete genome sequence of the endosymbiont blattabacterium from the cockroach nauphoe...
19935659 - Automatic policing of biochemical annotations using genomic correlations.
2835369 - Two copies of the human apolipoprotein c-i gene are linked closely to the apolipoprotei...
16769689 - Genome-wide survey of transcription factors in prokaryotes reveals many bacteria-specif...
17066299 - Structural divergence between the human and chimpanzee genomes.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current protocols in protein science / editorial board, John E. Coligan ... [et al.]     Volume:  Chapter 2     ISSN:  1934-3663     ISO Abbreviation:  -     Publication Date:  2001 May 
Date Detail:
Created Date:  2008-04-22     Completed Date:  2008-06-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101287868     Medline TA:  Curr Protoc Protein Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  Unit2.1     Citation Subset:  IM    
George Mason University, Fairfax, Virginia, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cluster Analysis
Computational Biology / methods*
Databases, Protein
Proteins / genetics*
Sequence Alignment / methods
Sequence Analysis, Protein / methods*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  High-throughput screening for protein-protein interactions using yeast two-hybrid arrays.
Next Document:  Hydrophobicity profiles for protein sequence analysis.