| Computational fluid dynamics modeling of gas dispersion in multi impeller bioreactor. | |
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MedLine Citation:
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PMID: 20471599 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In the present study, experiments have been carried out to identify various flow regimes in a dual Rushton turbines stirred bioreactor for different gas flow rates and impeller speeds. The hydrodynamic parameters like fractional gas hold-up, power consumption and mixing time have been measured. A two fluid model along with MUSIG model to handle polydispersed gas flow has been implemented to predict the various flow regimes and hydrodynamic parameters in the dual turbines stirred bioreactor. The computational model has been mapped on commercial solver ANSYS CFX. The flow regimes predicted by numerical simulations are validated with the experimental results. The present model has successfully captured the flow regimes as observed during experiments. The measured gross flow characteristics like fractional gas hold-up, and mixing time have been compared with numerical simulations. Also the effect of gas flow rate and impeller speed on gas hold-up and power consumption have been investigated. |
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Authors:
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Syed Ubaid Ahmed; Panneerselvam Ranganathan; Ashok Pandey; Savithri Sivaraman |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-01-19 |
Journal Detail:
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Title: Journal of bioscience and bioengineering Volume: 109 ISSN: 1347-4421 ISO Abbreviation: J. Biosci. Bioeng. Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-05-17 Completed Date: 2010-07-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888800 Medline TA: J Biosci Bioeng Country: Japan |
Other Details:
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Languages: eng Pagination: 588-97 Citation Subset: IM |
Copyright Information:
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(c) 2009 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved. |
Affiliation:
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Biotechnology Division, National Institute for Interdisciplinary Science and Technology (CSIR), Trivandrum-695 019, India. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Bioreactors* Computer Simulation Gases Models, Chemical* |
| Chemical | |
Reg. No./Substance:
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0/Gases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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