Document Detail

Computational estimation of fluid mechanical benefits from a fluid deflector at the distal end of artificial vascular grafts.
MedLine Citation:
PMID:  23260571     Owner:  NLM     Status:  MEDLINE    
Intimal hyperplasia at the distal anastomosis is considered to be an important determinant for arterial and arteriovenous graft failure. The connection between unhealthy hemodynamics and intimal hyperplasia motivates the use of computational fluid dynamics modeling to search for improved graft design. However, studies on the fluid mechanical impact on intimal hyperplasia at the suture line intrusion have previously been scanty. In the present work, we focus on intimal hyperplasia at the suture line and illustrate potential benefits from the introduction of a fluid deflector to shield the suture line from unhealthily high wall shear stress.
M W Roos; E Wadbro; M Berggren
Publication Detail:
Type:  Journal Article     Date:  2012-12-20
Journal Detail:
Title:  Computers in biology and medicine     Volume:  43     ISSN:  1879-0534     ISO Abbreviation:  Comput. Biol. Med.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-21     Completed Date:  2013-08-26     Revised Date:  2013-12-19    
Medline Journal Info:
Nlm Unique ID:  1250250     Medline TA:  Comput Biol Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  164-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
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MeSH Terms
Arteriovenous Anastomosis / physiopathology
Biomechanical Phenomena / physiology
Blood Vessel Prosthesis*
Computer Simulation
Hemodynamics / physiology
Hyperplasia / physiopathology
Image Processing, Computer-Assisted
Models, Cardiovascular*
Regional Blood Flow / physiology
Signal Processing, Computer-Assisted
Stress, Mechanical
Tunica Intima / physiology
Vascular Grafting / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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