| Computational cardiology: how computer simulations could be used to develop new therapies and advance existing ones. | |
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MedLine Citation:
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PMID: 23104919 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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This article reviews the latest developments in computational cardiology. It focuses on the contribution of cardiac modelling to the development of new therapies as well as the advancement of existing ones for cardiac arrhythmias and pump dysfunction. Reviewed are cardiac modelling efforts aimed at advancing and optimizing existent therapies for cardiac disease (defibrillation, ablation of ventricular tachycardia, and cardiac resynchronization therapy) and at suggesting novel treatments, including novel molecular targets, as well as efforts to use cardiac models in stratification of patients likely to benefit from a given therapy, and the use of models in diagnostic procedures. |
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Authors:
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Natalia A Trayanova; Thomas O'Hara; Jason D Bayer; Patrick M Boyle; Kathleen S McDowell; Jason Constantino; Hermenegild J Arevalo; Yuxuan Hu; Fijoy Vadakkumpadan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology Volume: 14 Suppl 5 ISSN: 1532-2092 ISO Abbreviation: Europace Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-10-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100883649 Medline TA: Europace Country: England |
Other Details:
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Languages: eng Pagination: v82-v89 Citation Subset: IM |
Affiliation:
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Department of Biomedical Engineering, Institute for Computational Medicine , Johns Hopkins University, Baltimore, MD, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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