| Comprehensive assessment of ventilatory functions of patients with chronic heart failure. | |
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MedLine Citation:
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PMID: 10786199 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: A comprehensive assessment of the ventilatory functions of patients with chronic heart failure (CHF) both at rest and during a cardiopulmonary exercise test (CPET). We studied 42 males, divided into two groups--patients with CHF (n = 21) and age, weight, height and BMI matched healthy controls (n = 21). All subjects underwent a symptom-limited ramp CPET, arterial blood gas analysis, and complex functional examination of the pulmonary system. Subjective rating of dyspnea and exertion were measured by the Borg and ATS dyspnea scales. CHF patients showed a slight, but statistically significant decrease of the spirographic and diffusion parameters, as well as of the indices of respiratory muscle strength. There were no changes in blood gases and in tidal breathing parameters. The exercise capacity was markedly reduced (VO2peak ml.min-1 1352 +/- 335 CHF patients vs 2077 +/- 276 healthy controls; p < 0.001) and the anaerobic threshold occurred earlier (< 40% of predicted VO2peak) during CPET in CHF patients. The increase in VE/VCO2 in CHF patients (35.7 +/- 5.1 CHF; 28.9 +/- 2.5 HC, p < 0.001) indicates a compromised ventilatory efficiency which leads to a higher dyspneic cost of exercise (Borg peak 9.5 +/- 1.03 CHF; 6.0 +/- 1.28 HC; p < 0.001) as compared with healthy controls. |
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Authors:
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M Tokmakova; S Kostianev; B Dobreva; A Djurdjev |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Folia medica Volume: 41 ISSN: 0204-8043 ISO Abbreviation: Folia Med (Plovdiv) Publication Date: 1999 |
Date Detail:
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Created Date: 2000-05-09 Completed Date: 2000-05-09 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 2984761R Medline TA: Folia Med (Plovdiv) Country: BULGARIA |
Other Details:
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Languages: eng Pagination: 12-8 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, Higher Medical Institute, Plovdiv, Bulgaria. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cardiac Output, Low / physiopathology* Chronic Disease Exercise Test Humans Male Middle Aged Respiration* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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