Document Detail


Compound dual radiation action theory for 252Cf brachytherapy.
MedLine Citation:
PMID:  15353749     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The existing dosimetry protocol that uses the concept of RBE for 252Cf brachytherapy contains large uncertainties. A new formula has been developed to correlate the biological effect (i.e. cell survival fraction) resulting from a mixed n + gamma radiation field with two physical quantities and two biological quantities. The formula is based on a pathway model evolved from that of the compound-dual-radiation-action (CDRA) theory, previously proposed by Rossi and Zaider. The new model employs the recently published data on radiation-induced DNA lesions. The new formula is capable of predicting quantitatively the synergistic effect caused by the interactions between neutron events and gamma ray events, and it is intended to be included into a new dosimetry protocol for future 252Cf brachytherapy.
Authors:
C K Wang; X Zhang
Related Documents :
17278489 - Multiple-estimate monte carlo calculation of the dose rate constant for a cesium-131 in...
1996379 - The observed relationship between the occurrence of acute radiation effects and leukemi...
17309869 - Analysis of a case of internal contamination with cobalt radioisotopes.
23254689 - A contralesional eeg power increase mediated by interhemispheric disconnection provides...
11548339 - Electronic look-up tables on retention and excretion of radionuclides as a pc based sup...
2043249 - Verification of optical distance indicator accuracy.
21406429 - Indoor exposure of population to radon in the fyr of macedonia.
24772039 - A hybrid monkey search algorithm for clustering analysis.
22074819 - Lipschitz-killing curvature based expected euler characteristics for p-value correction...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiation protection dosimetry     Volume:  110     ISSN:  0144-8420     ISO Abbreviation:  Radiat Prot Dosimetry     Publication Date:  2004  
Date Detail:
Created Date:  2004-09-08     Completed Date:  2004-12-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8109958     Medline TA:  Radiat Prot Dosimetry     Country:  England    
Other Details:
Languages:  eng     Pagination:  801-6     Citation Subset:  IM    
Affiliation:
Nuclear & Radiological Engineering Program, Georgia Institute of Technology, Neely Research Center, 900 Atlantic Drive, Atlanta, GA 30332-0425, USA. chris.wang@nre.gatech.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Algorithms
Body Burden
Brachytherapy / adverse effects,  methods*
Californium / adverse effects,  therapeutic use*
Cell Survival / radiation effects
Computer Simulation
DNA / radiation effects*
DNA Damage
Dose-Response Relationship, Radiation
Gamma Rays / adverse effects,  therapeutic use*
Models, Biological*
Neutrons / adverse effects,  therapeutic use*
Radiation Protection / methods
Radiometry / methods*
Radiotherapy Dosage
Relative Biological Effectiveness
Risk Assessment / methods
Risk Factors
Chemical
Reg. No./Substance:
7440-71-3/Californium; 9007-49-2/DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Recent advances of nanodosimetry.
Next Document:  Neutron absorbed dose determination by calculations of recoil energy.