Document Detail

Compositional changes of the aortic valve similar to the artery with aging.
MedLine Citation:
PMID:  12117235     Owner:  NLM     Status:  MEDLINE    
To elucidate compositional changes of the cardiac valves with aging, the authors investigated the relationships among element contents in the aortic valves, in which the accumulation of calcium and phosphorus was the highest. The subjects consisted of 10 men and 14 women, ranging in age from 65 to 102 yr. Extremely significant direct correlations were found among the contents of calcium, phosphorus, magnesium, sodium, and zinc in the aortic valves. In contrast, significant inverse correlations were found between the contents of sulfur and the other elements, such as calcium, phosphorus, magnesium, and sodium. It should be noted that these correlations present in the aortic valves were very similar to those in the arteries, especially those in the thoracic aortas. The changes of the mass ratios of Mg/Ca and Mg/P in the aortic valves were similar to those in the thoracic aortas. As calcium and phosphorus increased in the aortic valve, the mass ratios Mg/Ca and Mg/P decreased reversely in the aortic valve. These results suggest that the compositional change of the aortic valve is very similar to that of the thoracic aorta.
Setsuko Tohno; Yoshiyuki Tohno; Yumi Moriwake; Cho Azuma; Yoshiaki Ohnishi; Takeshi Minami
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biological trace element research     Volume:  87     ISSN:  0163-4984     ISO Abbreviation:  Biol Trace Elem Res     Publication Date:  2002  
Date Detail:
Created Date:  2002-07-15     Completed Date:  2002-12-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7911509     Medline TA:  Biol Trace Elem Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  83-93     Citation Subset:  IM    
Department of Anatomy, Nara Medical University, Kashihara, Japan.
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MeSH Terms
Aged, 80 and over
Aorta / anatomy & histology*
Aortic Valve / anatomy & histology*
Trace Elements / metabolism*
Reg. No./Substance:
0/Trace Elements

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