Document Detail


Composition of rat milk from day 5 to 20 of lactation and milk intake of lean and preobese Zucker pups.
MedLine Citation:
PMID:  7193715     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Milk composition and milk intake were measured in lean and preobese Zucker rat pups. Lactating dams were injected with 3H2O, which equilibrated with plasma water within 30 minutes. A constant specific activity of 3H was maintained by adding 3H2O to drinking water. Blood samples of 5 microliters were obtained from 1, 15 and 20-day-old suckling pups every 4 hours for a 24-hour period and the accumulation of tritium was used to calculate pups' milk intake. No diurnal variation in milk intake of pups was observed. Obese pups were identified at 5 weeks of age and showed no difference in milk intake compared to lean littermates at 10, 15 and 20 days of age. Milk intake of pups increased with age from 2.0 ml at day 10 to 15.8 ml by day 20. Food and water intake of dams also increased from day 10 to 20 of lactation. The protein and carbohydrate component of rat milk did not change significantly from day 5 to 20 of lactation; however, the fat component decreased significantly from 12.7% at day 5 to 4.2% at day 20.
Authors:
V Y Godbole; M L Grundleger; T A Pasquine; S W Thenen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of nutrition     Volume:  111     ISSN:  0022-3166     ISO Abbreviation:  J. Nutr.     Publication Date:  1981 Mar 
Date Detail:
Created Date:  1981-05-13     Completed Date:  1981-05-13     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0404243     Medline TA:  J Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  480-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Animals, Suckling / metabolism
Body Water / metabolism
Drinking
Eating
Female
Lactation
Milk / metabolism*
Obesity / genetics,  metabolism,  veterinary*
Pregnancy
Rats / metabolism*
Rodent Diseases / genetics,  metabolism
Time Factors
Grant Support
ID/Acronym/Agency:
AM 00106/AM/NIADDK NIH HHS; AM 02911/AM/NIADDK NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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