Document Detail

Composition of postnatal weight loss & subsequent weight gain in preterm infants.
MedLine Citation:
PMID:  7751046     Owner:  NLM     Status:  MEDLINE    
To investigate the changes in body composition corresponding to postnatal weight loss and regaining of birth weight, total body water (TBW) and extracellular water (ECW) were measured at birth, on the day of maximum weight loss and on regaining of birth weight in 23 preterm appropriate for gestational age (AGA) infants (mean +/- SD birth weight 1902 +/- 242 g, gestational age 236 +/- 7 days). Intracellular water (ICW) was determined by the difference between TBW and ECW and body solids by the difference between TBW and body weight. Almost 90 per cent of early postnatal weight loss of 132 +/- 38 g (6.9% of birth weight) was because of loss of body water (117 +/- 30 ml; 7.9% of TBW at birth). ECW loss (mean +/- SD 106 +/- 35 ml) accounted for 90 per cent of the TBW loss. Of the subsequent weight gain (134 +/- 40 g) till regaining of birth weight, 48 per cent (64 +/- 28 ml) was TBW and 52 per cent (70 +/- 13 g) body solids. The major gain in body water was in ICW (47 +/- 21 ml). A gradual decrease in TBW and ECW, and a gain in ICW and body solids per kg body weight was observed throughout the study period. These findings favour the concept that in preterm (31-36 wk) infants (i) postnatal weight loss is primarily a reflection of ECW loss and subsequent weight gain is because of cellular growth, (ii) postnatal loss of ECW continues even when weight gain and accumulation of body solids has started.
S Singhi; V Sood; O N Bhakoo; N K Ganguly; A Kaur
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Indian journal of medical research     Volume:  101     ISSN:  0971-5916     ISO Abbreviation:  Indian J. Med. Res.     Publication Date:  1995 Apr 
Date Detail:
Created Date:  1995-06-22     Completed Date:  1995-06-22     Revised Date:  2013-04-18    
Medline Journal Info:
Nlm Unique ID:  0374701     Medline TA:  Indian J Med Res     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  157-62     Citation Subset:  IM    
Department of Paediatrics, Postgraduate Institute of Medical Education & Research, Chandigarh.
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MeSH Terms
Birth Weight*
Body Water
Infant, Newborn
Infant, Premature*
Weight Gain*
Weight Loss*

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