Document Detail


Composition of acidic glycosaminoglycans in human term placenta blood vessels.
MedLine Citation:
PMID:  539916     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The composition of acidic glycosaminoglycans in pooled blood vessels, mostly of fetal origin, from a normal human term placenta was investigated by a series of procedures consisting of chromatography on a cetyl pyridinium chloride-cellulose column, cellulose acetate electrophoresis, susceptibility to testicular hyaluronidase and thin layer chromatography of the products of digestion with bacterial chondroitinases. The results indicate the presence of hyaluronic acid (36%), chondroitin-6-sulfate (27%), dermatan sulfate (21%), heparan sulfate (8%) and chondroitin-4-sulfate (8%). Several of the fractions obtained from the cetyl pyridinium chloride-cellulose column exhibited anticoagulant activity, which might be physiological importance for the maintainance of the fluidity of the intensively circulating placental blood.
Authors:
L Wasserman; A Ber; J A Goldman; D Allalouf
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Artery     Volume:  5     ISSN:  0098-6127     ISO Abbreviation:  Artery     Publication Date:  1979 Jan 
Date Detail:
Created Date:  1980-05-14     Completed Date:  1980-05-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7508494     Medline TA:  Artery     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  45-60     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Blood Vessels / analysis*
Carbohydrates / analysis
Chondroitin Sulfates / analysis
Dermatan Sulfate / analysis
Female
Glycosaminoglycans / analysis*
Heparitin Sulfate / analysis
Hexosamines / analysis
Humans
Hyaluronic Acid / analysis
Keratan Sulfate / analysis
Placenta / blood supply*
Pregnancy
Proteins / analysis
Uronic Acids / analysis
Chemical
Reg. No./Substance:
0/Carbohydrates; 0/Glycosaminoglycans; 0/Hexosamines; 0/Proteins; 0/Uronic Acids; 24967-94-0/Dermatan Sulfate; 9004-61-9/Hyaluronic Acid; 9007-28-7/Chondroitin Sulfates; 9050-30-0/Heparitin Sulfate; 9056-36-4/Keratan Sulfate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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