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Composite Stent-Grafts Are Not Associated With Increased Endoleak or Reintervention Rates After Endovascular Abdominal Aneurysm Repair.
MedLine Citation:
PMID:  22998790     Owner:  NLM     Status:  Publisher    
BACKGROUND: Although present-generation endografts have expanded the indications for endovascular abdominal aneurysm repair, arterial anatomy frequently dictates the use of a combination of commercially available endografts and components for successful aneurysm repair. This study sought to determine whether there was an increase in endoleak or secondary intervention rates in individuals treated with composite endografts compared with noncomposite, or standard, endografts. METHODS: From 1999 to 2009, 421 endovascular abdominal aneurysm repairs were performed at a single institution. A total of 384 patients met criteria for inclusion, with at least one follow-up imaging study. Patients were then identified as having had a composite endograft, defined as any combination of two or more different commercially available endograft or stent components, versus a standard endograft. Primary outcomes measured were freedom from endoleak and secondary intervention. RESULTS: During the study period, 60 composite endograftings and 324 standard endograftings were performed. The groups were well matched for demographics, including age, gender, comorbidities, emergent need for procedure, and 30-day mortality (1.64% vs. 1.54%, nonsignificant). Median follow-up was 16.3 months (range, 19 days to 8.5 years) and 10.2 months (range, 4 days to 8.7 years) for composite and standard endografts, respectively. There was no significant difference between the groups in either endoleak or secondary intervention rates. Median time to endoleak detection was 2.0 months (range, 2 days to 3.9 years) for composite endografts and 2.8 months (range, 2 days to 6.9 years) for standard endografts. Median time to secondary intervention was 7.0 months (range, 4 days to 6.9 years) for composite endografts and 6.7 months (range, 1 day to 6.7 years) for standard endografts. CONCLUSIONS: Composite endografts, namely, the combination of different commercially available endografts or stents used for the treatment of aortic aneurysms, are not associated with increased mortality, endoleak, or secondary intervention rates compared with noncomposite endografts.
Julia T Saraidaridis; Nicholas H Osborne; Jonathan L Eliason; Enrique Criado; David M Williams; Narasimham L Dasika; Gilbert R Upchurch; John E Rectenwald
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-18
Journal Detail:
Title:  Annals of vascular surgery     Volume:  -     ISSN:  1615-5947     ISO Abbreviation:  Ann Vasc Surg     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8703941     Medline TA:  Ann Vasc Surg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Annals of Vascular Surgery Inc. Published by Elsevier Inc. All rights reserved.
The Section of Vascular Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI.
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