| Complications of radical nephrectomy for renal cell carcinoma: a retrospective study comparing transperitoneal and retroperitoneal approaches using a standardized reporting methodology in two Chinese centers. | |
| | |
MedLine Citation:
|
PMID: 23298461 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
The reporting of complications following transperitoneal and retroperitoneal open radical nephrectomy (RN) is nonstandardized. The aim of this study was to compare early complications between the two approaches using a standardized reporting methodology in a large contemporary cohort. Between 1996 and 2009, 558 patients underwent open RN for renal cell carcinoma (RCC) in our two centers. Records were reviewed for clinicopathological features and complications. Complications were graded using the Clavien system based on the severity of impact. One hundred and five patients (18.8%) had one or more early complications (168 complications overall). The overall rates of grade I to V complications were 5.6%, 10.8%, 2.2%, 0.4%, and 0.2%, respectively. Patients who underwent transperitoneal RN did not experience more overall or procedure-related complications than those who underwent retroperitoneal RN (P = 0.911 and P = 0.851, respectively). On subgroup analysis, neither grade I/II nor grade III-V complications were significantly different between the transperitonal RN and retroperitoneal RN groups. Multivariate analysis showed that for any grade of complication, age (P = 0.016) and estimated blood loss (P = 0.001) were significant predictors. We concluded that open RN is a safe procedure associated with low rates of serious morbidity and mortality. Compared with retroperitoneal RN, transperitoneal RN was not associated with more complications. Older patient age and more blood loss at surgery were independent predictors for higher early postoperative complication rates. |
| | |
Authors:
|
Zhi-Ling Zhang; Yong-Hong Li; Jun-Hang Luo; Zhuo-Wei Liu; Kai Yao; Pei Dong; Hui Han; Zi-Ke Qin; Wei Chen; Fang-Jian Zhou |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2013-1-9 |
Journal Detail:
|
Title: Chinese journal of cancer Volume: - ISSN: 1944-446X ISO Abbreviation: Chin J Cancer Publication Date: 2013 Jan |
Date Detail:
|
Created Date: 2013-1-9 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101498232 Medline TA: Chin J Cancer Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
State Key Laboratory of Oncology in South China; Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, P. R. China zhoufj@mail.sysu.edu.cn. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cholesterol reduction ameliorates glucose-induced calcium handling and insulin secretion in islets f...
Next Document: Discovery of molecular associations among aging, stem cells, and cancer based on gene expression pro...