| Complications and conversions in myeloproliferative disorders: an analysis of 356 cases. | |
| | |
MedLine Citation:
|
PMID: 12411064 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To investigate the complications and conversions in myeloproliferative disorders (MPD). METHODS: Three hundred and fifty six patients with MPD were reviewed, including 78 with etiologic thrombocythemia (ET), 93 with primary myelofibrosis (MF), 185 with polythythemia vera (PV). The clinical observation, follow-up, analysis with SPSS statistic software were performed. RESULTS: Out of the 356 cases, 101 (28.5%) developed thromboembolic events, 81 (22.8%) hemorrhage, 60 (16.9%) hypertension, 20 (5.6%) coronary heart disease, 3 (0.8%) hemolysis and 1 (0.3%) gastrointestinal ulcer, 2 (0.6%) calculus and 1 (0.3%) bone marrow necrosis. Twenty four patients (6.7%) developed MF (9 in ET, 15 in PV), 2 (0.6%) erythrocytosis (1 in ET, 1 in MF), 3 (0.8%) thrombocythemia (all in PV), 5 (1.4%) acute leukemia (2 in ET, 3 in MF) and 1 (0.3%) multiple myeloma (in ET). Eleven cases (3.1%) died, 5 (1.4%) from acute leukemia, 2 (0.6%) fatal hemorrhages, 1 (0.3%) each myocardial infarction and infectious shock, 2 (0.6%) unknown causes. CONCLUSION: Embolism and bleeding were the main complications in MPD. Conversions among ET, MF and PV hematological malignancies could occur. |
| | |
Authors:
|
Yi Wang; Anlan Zuo; Yinghui Liu; Bingcheng Liu; Changlai Hao; Lihong Wang; Xueli Zhou; Linsheng Qian |
Related Documents
:
|
17350984 - Internal atrial shock delivery by standard diagnostic electrophysiology catheters in go... 18655944 - The use of vasopressors and inotropes in the emergency medical treatment of shock. 12785014 - Cardiac ucp2 expression and myocardial oxidative metabolism during acute septic shock i... 3995694 - The effect of hyperdynamic sepsis on myocardial performance. 10487494 - The effects of dyslipidemia on left ventricular systolic function in patients with stab... 17643924 - Left ventricular restoration: how important is the surgical treatment of ischemic heart... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi Volume: 23 ISSN: 0253-2727 ISO Abbreviation: Zhonghua Xue Ye Xue Za Zhi Publication Date: 2002 Jun |
Date Detail:
|
Created Date: 2002-11-04 Completed Date: 2002-12-17 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8212398 Medline TA: Zhonghua Xue Ye Xue Za Zhi Country: China |
Other Details:
|
Languages: eng Pagination: 314-7 Citation Subset: IM |
Affiliation:
|
Institute of Hematology, CAMS and PUMC, Tianjin 300020, China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Aged, 80 and over Child Female Humans Male Middle Aged Myeloproliferative Disorders / complications*, mortality |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The relationship between myelodysplastic syndromes and autoimmune disorders.
Next Document: Meta-analysis on the relationship between children's intelligence and factors as iodine deficiency, ...