Document Detail

Complications associated with catheter ablation of atrial fibrillation.
MedLine Citation:
PMID:  17534254     Owner:  NLM     Status:  MEDLINE    
Atrial fibrillation is the most common clinical arrhythmia, affecting millions of people worldwide and utilizing billions of dollars annually in heath care costs associated with the disease. Catheter based ablation, centering around the electrical isolation of the pulmonary veins, has emerged as a viable treatment option for patients with symptomatic paroxysmal or persistent atrial fibrillation. Because of the complex nature of the procedure, there are a number of potential complications which can occur which are related to problems with vascular access, mechanical complications resulting from catheter manipulation within the heart, cardioembolic complications, and complications arising from the effects of radiofrequency ablations in the left atrium. The most frequent complications arise from pseudoaneurysms, arterio-venous fistulas, hematomas, neurologic events (stroke and transient ischemic attacks), and pericardial effusion/tamponade. An evolving understanding of the risks of the procedure have helped to minimize complications by changing ablation strategies to avoid lesion delivery within the veins, emphasizing careful attention during the procedure to anticoagulation, utilizing intracardiac ultrasound and electroanatomic mapping systems for better visualization of intracardiac structures, and recognizing complications promptly during and after the procedure. Hopefully, improved techniques in the future will help to further improve the safety of catheter ablation of atrial fibrillation to allow for continued growth of this procedure.
S Dhruvakumar; E P Gerstenfeld
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Minerva cardioangiologica     Volume:  55     ISSN:  0026-4725     ISO Abbreviation:  Minerva Cardioangiol     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-05-30     Completed Date:  2007-10-09     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0400725     Medline TA:  Minerva Cardioangiol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  353-68     Citation Subset:  IM    
Division of Cardiology, Department of Medicine, University of Pennsylvania Health System, Philadelphia, PA, USA.
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MeSH Terms
Aneurysm, False / etiology
Arteriovenous Fistula / etiology
Atrial Fibrillation / surgery*
Cardiac Tamponade / etiology
Catheter Ablation / adverse effects*
Hematoma / etiology
Ischemic Attack, Transient / etiology
Pericardial Effusion / etiology
Postoperative Complications / etiology*
Risk Factors
Stroke / etiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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