| Complications after liver transplantation: evaluation with magnetic resonance imaging, magnetic resonance cholangiography, and 3-dimensional contrast-enhanced magnetic resonance angiography in a single session. | |
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MedLine Citation:
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PMID: 19385153 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate a comprehensive magnetic resonance imaging (MRI) protocol as noninvasive diagnostic modality for simultaneous detection of parenchymal, biliary, and vascular complications after liver transplantation. METHODS: Fifty-two liver transplant recipients suspected to have parenchymal, biliary, and (or) vascular complications underwent our MRI protocol at 1.5T unit using a phased array coil. After preliminary acquisition of axial T1w and T2w sequences, magnetic resonance cholangiography (MRC) was performed through a breath-hold, thin- and thick-slab, single-shot T2w sequence in the coronal plane. Contrast-enhanced magnetic resonance angiography (CEMRA) was obtained using a 3-dimensional coronal spoiled gradient-echo sequence, which enabled acquisition of 32 partitions 2.0 mm thick. A fixed dose of 20 ml gadobenate dimeglumine was administered at 2 mL/s. A post-contrast T1w sequence was also performed. Two observers in conference reviewed source images and 3-dimensional reconstructions to determine the presence of parenchymal, biliary, and vascular complications. MRI findings were correlated with surgery, endoscopic retrograde cholangiography (ERC), biopsy, digital subtraction angiography (DSA), and imaging follow-up. RESULTS: MRI revealed abnormal findings in 32 out of 52 patients (61%), including biliary complications (anastomotic and nonanastomotic strictures, and lithiasis) in 31, vascular disease (hepatic artery stenosis and thrombosis) in 9, and evidence of hepatic abscess and hematoma in 2. ERC confirmed findings of MRC in 30 cases, but suggested disease underestimation in 2. DSA confirmed 7 magnetic resonance angiogram (MRA) findings, but suggested disease overestimation in 2. CONCLUSION: MRI combined with MRC and CEMRA can provide a comprehensive assessment of parenchymal, biliary, and vascular complications in most recipients of liver transplantation. |
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Authors:
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Piero Boraschi; Francescamaria Donati; Roberto Gigoni; Simonetta Salemi; Lucio Urbani; France Filipponi; Fabio Falaschi; Carlo Bartolozzi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes Volume: 59 ISSN: 0846-5371 ISO Abbreviation: Can Assoc Radiol J Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2009-04-23 Completed Date: 2009-05-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8812910 Medline TA: Can Assoc Radiol J Country: Canada |
Other Details:
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Languages: eng Pagination: 259-63 Citation Subset: IM |
Affiliation:
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Second Department of Radiology, Pisa University Hospital, Via Paradisa 2, 56124 Pisa, Italy. p.boraschi@do.med.unipi.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Angiography Bile Duct Diseases / diagnosis Cholangiography Contrast Media / diagnostic use Female Hematoma / diagnosis Humans Imaging, Three-Dimensional Liver Abscess / diagnosis Liver Transplantation* Magnetic Resonance Imaging / methods* Male Meglumine / analogs & derivatives, diagnostic use Middle Aged Organometallic Compounds / diagnostic use Postoperative Complications Vascular Diseases / diagnosis |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Organometallic Compounds; 113662-23-0/gadobenic acid; 6284-40-8/Meglumine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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