Document Detail

Compliance with postpartum Rh isoimmunization prophylaxis in Alberta.
MedLine Citation:
PMID:  2996738     Owner:  NLM     Status:  MEDLINE    
A retrospective review of obstetric records for 1979 in two major Calgary hospitals was undertaken to determine the rate of compliance with postpartum Rh isoimmunization prophylaxis in Alberta. The charts of 4528 women ranging in age from 13 to 46 years were reviewed. The prevalence rate of Rh negativity was found to be 16%. Of the 710 Rh-negative women 490 (69%) were eligible to receive Rh immune globulin (RhIG); that is, they had no anti-D antibodies, and the baby/fetus was Rh-positive or Rh-unknown. RhIG had been administered to 93.6% of the eligible women; the compliance rate ranged from 66.7% for obstetric emergencies (i.e., spontaneous abortion, antepartum or early-pregnancy hemorrhage, or ectopic pregnancy) to 98.2% for postpartum diagnoses. In more than half (54.7%) of the women who underwent amniocentesis Rh type was not determined; the implications of this finding are discussed. Although poor compliance with postpartum RhIG administration is not a reason for withholding antepartum administration of RhIG, maximum compliance with the more cost-effective programs should be attained before antepartum programs are fully implemented.
S Huchcroft; P Gunton; T Bowen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne     Volume:  133     ISSN:  0820-3946     ISO Abbreviation:  CMAJ     Publication Date:  1985 Nov 
Date Detail:
Created Date:  1985-12-09     Completed Date:  1985-12-09     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9711805     Medline TA:  CMAJ     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  871-5     Citation Subset:  AIM; IM    
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MeSH Terms
Blood Group Incompatibility / epidemiology
Immunoglobulins / administration & dosage*
Infant, Newborn
Patient Compliance*
Postpartum Period*
Pregnancy Complications, Hematologic / epidemiology
Referral and Consultation
Retrospective Studies
Rh Isoimmunization / prevention & control*
Rh-Hr Blood-Group System
Rho(D) Immune Globulin
Reg. No./Substance:
0/Immunoglobulins; 0/Rh-Hr Blood-Group System; 0/Rho(D) Immune Globulin

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