Document Detail


Compliance to the CONSORT statement of randomized controlled trials in solid organ transplantation: a 3-year overview.
MedLine Citation:
PMID:  23279054     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The Consolidated Standards of Reporting Trials (CONSORT) statement was developed to improve the reporting quality of randomized controlled trials (RCTs). Our primary aim was to assess to what extent reports of RCTs in solid organ transplantation adhere to the 2010 CONSORT statement. Secondly, we investigated the relationship between CONSORT adherence, methodological quality and some other factors. We included 290 RCTs that were published between 2007 and 2009. We examined to what extent trial reports complied with 30 items of the CONSORT statement. Methodological quality was evaluated using the Jadad scale plus allocation concealment and whether data analysis was by randomized group (intention to treat). On average, trial reports addressed 47% of the CONSORT items. Forty-three per cent of RCTs was considered to be of good quality according to Jadad scale, and the items allocation concealment and data analysis were satisfied in approximately one-third of trials. Good quality RCTs reported on more CONSORT items than poor quality trials. The methodological quality and adherence to the CONSORT statement of RCTs published in journals that endorse the CONSORT statement was superior to those in journals without CONSORT endorsement. Overall compliance with the CONSORT statement and the methodological quality of RCTs in organ transplantation remains unsatisfactory.
Authors:
Liang Q Liu; Peter J Morris; Liset H M Pengel
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Publication Detail:
Type:  Comparative Study; Journal Article; Review     Date:  2013-01-02
Journal Detail:
Title:  Transplant international : official journal of the European Society for Organ Transplantation     Volume:  26     ISSN:  1432-2277     ISO Abbreviation:  Transpl. Int.     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-14     Completed Date:  2013-08-20     Revised Date:  2013-10-03    
Medline Journal Info:
Nlm Unique ID:  8908516     Medline TA:  Transpl Int     Country:  England    
Other Details:
Languages:  eng     Pagination:  300-6     Citation Subset:  IM    
Copyright Information:
© 2013 The Authors Transplant International © 2013 European Society for Organ Transplantation. Published by Blackwell Publishing Ltd.
Affiliation:
Centre for Evidence in Transplantation, Clinical Effectiveness Unit, Royal College of Surgeons of England and the London School of Hygiene and Tropical Medicine, University of London, London, UK.
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MeSH Terms
Descriptor/Qualifier:
Female
Graft Rejection
Graft Survival
Great Britain
Guideline Adherence / statistics & numerical data*
Humans
Incidence
Male
Needs Assessment
Organ Transplantation / standards*,  statistics & numerical data
Practice Guidelines as Topic / standards*
Quality Control
Randomized Controlled Trials as Topic / standards*
Retrospective Studies
Comments/Corrections
Comment In:
Transpl Int. 2013 Sep;26(9):e87   [PMID:  23725017 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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