Document Detail

Compliance measurement in respiratory distress syndrome: the prediction of outcome.
MedLine Citation:
PMID:  3808775     Owner:  NLM     Status:  MEDLINE    
Dynamic compliance (Cdyn) measurements within the first three days of life predicted survival in 60 preterm infants suffering from respiratory distress syndrome. Cdyn was measured in 47 survivors at 2.3 +/- 1.4 days of life and in 13 nonsurvivors on 2.7 +/- 1.7 days. All nonsurvivors died from respiratory failure within the first two weeks of life. Mean Cdyn of the survivors was 0.83 +/- 0.33 ml/cm H2O and of the nonsurvivors 0.35 +/- 0.19 ml/cm H2O (p less than 0.001). Cdyn values below 0.45 ml/cm H2O predicted 11 of 13 deaths in infants, and Cdyn measurements above this value predicted 45 of 47 survivals, with a specificity of 81% and a sensitivity of 89%. Eleven of the survivors, who subsequently developed bronchopulmonary dysplasia (BPD), had a mean Cdyn of 0.56 +/- 0.23 ml/cm H2O. When these infants were matched with infants of comparable weight without evidence of BPD, the BPD group had a significantly lower Cdyn (p less than 0.05). Cdyn measurements during the first three days of life are useful in predicting outcome of respiratory failure secondary to respiratory distress syndrome.
M A Graff; R P Novo; M Diaz; C Smith; I M Hiatt; T Hegyi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric pulmonology     Volume:  2     ISSN:  8755-6863     ISO Abbreviation:  Pediatr. Pulmonol.     Publication Date:    1986 Nov-Dec
Date Detail:
Created Date:  1987-03-12     Completed Date:  1987-03-12     Revised Date:  2006-03-28    
Medline Journal Info:
Nlm Unique ID:  8510590     Medline TA:  Pediatr Pulmonol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  332-6     Citation Subset:  IM    
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MeSH Terms
Airway Resistance
Birth Weight
Follow-Up Studies
Infant, Newborn
Lung Compliance*
Respiratory Distress Syndrome, Newborn / diagnosis*,  mortality

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