Document Detail


Compliance measurement in respiratory distress syndrome: the prediction of outcome.
MedLine Citation:
PMID:  3808775     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Dynamic compliance (Cdyn) measurements within the first three days of life predicted survival in 60 preterm infants suffering from respiratory distress syndrome. Cdyn was measured in 47 survivors at 2.3 +/- 1.4 days of life and in 13 nonsurvivors on 2.7 +/- 1.7 days. All nonsurvivors died from respiratory failure within the first two weeks of life. Mean Cdyn of the survivors was 0.83 +/- 0.33 ml/cm H2O and of the nonsurvivors 0.35 +/- 0.19 ml/cm H2O (p less than 0.001). Cdyn values below 0.45 ml/cm H2O predicted 11 of 13 deaths in infants, and Cdyn measurements above this value predicted 45 of 47 survivals, with a specificity of 81% and a sensitivity of 89%. Eleven of the survivors, who subsequently developed bronchopulmonary dysplasia (BPD), had a mean Cdyn of 0.56 +/- 0.23 ml/cm H2O. When these infants were matched with infants of comparable weight without evidence of BPD, the BPD group had a significantly lower Cdyn (p less than 0.05). Cdyn measurements during the first three days of life are useful in predicting outcome of respiratory failure secondary to respiratory distress syndrome.
Authors:
M A Graff; R P Novo; M Diaz; C Smith; I M Hiatt; T Hegyi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric pulmonology     Volume:  2     ISSN:  8755-6863     ISO Abbreviation:  Pediatr. Pulmonol.     Publication Date:    1986 Nov-Dec
Date Detail:
Created Date:  1987-03-12     Completed Date:  1987-03-12     Revised Date:  2006-03-28    
Medline Journal Info:
Nlm Unique ID:  8510590     Medline TA:  Pediatr Pulmonol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  332-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Airway Resistance
Birth Weight
Follow-Up Studies
Humans
Infant, Newborn
Lung Compliance*
Prognosis
Respiratory Distress Syndrome, Newborn / diagnosis*,  mortality

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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