| Compliance effect on patency of small diameter vascular grafts. | |
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MedLine Citation:
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PMID: 2597533 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The compliance mismatch hypothesis as a cause of failure of small diameter grafts was investigated using 4 mm internal diameter, 5 cm long Biolized polyurethane grafts. The luminal surface of 0.5 mm thick Biomer sponge grafts was covered with 100 microns of crosslinked gelatin. Compliance matched, and noncompliant grafts had in vivo compliance values of 13.5 +/- 2.89 and 1.0 +/- 0.7 X 10(-2%) per mmHg, respectively. In vivo compliance defined as 2 X dD/dP X 1/Do was measured in situ using the ultrasonic Hokanson probe. Compliance values of compliant grafts equaled that of the canine carotid artery at 100 mmHg mean arterial pressure. Grafts were implanted using an end-to-end anastomosis in 14 dogs for 6 wk. Patency rates for compliant vs. noncompliant grafts were 64% (9/14) and 50% (7/14). Compliance values for compliant grafts decreased to a mean of 7.14 X 10(-2%) per mmHg. Anastomotic intimal hyperplasia at the proximal and distal ends of compliant and noncompliant grafts measured 239.9 +/- 128, 197 +/- 129 microns, 338.9 +/- 273.6, and 304.3 +/- 179.3 microns, respectively. There were no significant differences in localized anastomotic intimal hyperplasia at either graft end for either graft type. This study did not show any positive effects of graft compliance. |
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Authors:
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N Uchida; H Emoto; H Kambic; H Harasaki; J F Chen; S H Hsu; S Murabayashi; Y Nosé |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: ASAIO transactions / American Society for Artificial Internal Organs Volume: 35 ISSN: 0889-7190 ISO Abbreviation: ASAIO Trans Publication Date: 1989 Jul-Sep |
Date Detail:
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Created Date: 1990-02-06 Completed Date: 1990-02-06 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8611947 Medline TA: ASAIO Trans Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 556-8 Citation Subset: IM |
Affiliation:
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Department of Artificial Organs, Cleveland Clinic Foundation, OH 44195-5132. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anastomosis, Surgical Animals Blood Vessel Prosthesis* Carotid Arteries / surgery Compliance Dogs Graft Occlusion, Vascular / pathology* Muscle, Smooth, Vascular / pathology Polyurethanes* Prosthesis Design |
| Grant Support | |
ID/Acronym/Agency:
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R01 HL33257/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Polyurethanes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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