| Complex visual manifestations of posterior cortical atrophy. | |
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MedLine Citation:
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PMID: 23196944 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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ABSTRACT:: We describe 5 patients with complex visual disturbances in the absence of ocular pathology who were ultimately diagnosed with posterior cortical atrophy (PCA). The presence of visual cortical symptoms, neuroimaging findings and clinical evolution led to the diagnosis 1-5 years after the onset of visual symptoms. Age of onset ranged from 50-66 years. In 3 cases, magnetic resonance imaging (MRI) of the brain demonstrated predominantly right posterior cortical atrophy. The other 2 patients had nonspecific MRI findings but the diagnosis was established given the findings on clinical examination and positron emission tomography (PET). All progressed to global dementia and an autopsy confirmed the diagnosis of Alzheimer disease in one patient. The possibility of PCA should be considered when a patient presents with complex visual symptoms in the absence of ocular pathology. Early neurological assessment may avoid diagnostic delay. |
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Authors:
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Ramon Reñé; Silvia Muñoz; Jaume Campdelacreu; Jordi Gascon-Bayarri; Imma Rico; Montserrat Juncadella; Jordi Arruga |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society Volume: 32 ISSN: 1536-5166 ISO Abbreviation: J Neuroophthalmol Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2012-11-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9431308 Medline TA: J Neuroophthalmol Country: United States |
Other Details:
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Languages: eng Pagination: 307-12 Citation Subset: IM |
Affiliation:
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Departments of Neurology-Dementia Unit (RR, JC, JGB), Neuropsychology (IR, MJ), and Ophthalmology (SM, JA), Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Spain. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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