| Complex regulatory pathways coordinate cell-cycle progression and development in Caulobacter crescentus. | |
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MedLine Citation:
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PMID: 18929067 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Caulobacter crescentus has become the predominant bacterial model system to study the regulation of cell-cycle progression. Stage-specific processes such as chromosome replication and segregation, and cell division are coordinated with the development of four polar structures: the flagellum, pili, stalk, and holdfast. The production, activation, localization, and proteolysis of specific regulatory proteins at precise times during the cell cycle culminate in the ability of the cell to produce two physiologically distinct daughter cells. We examine the recent advances that have enhanced our understanding of the mechanisms of temporal and spatial regulation that occur during cell-cycle progression. |
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Authors:
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Pamela J B Brown; Gail G Hardy; Michael J Trimble; Yves V Brun |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review |
Journal Detail:
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Title: Advances in microbial physiology Volume: 54 ISSN: 0065-2911 ISO Abbreviation: Adv. Microb. Physiol. Publication Date: 2009 |
Date Detail:
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Created Date: 2008-10-20 Completed Date: 2008-12-30 Revised Date: 2010-12-03 |
Medline Journal Info:
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Nlm Unique ID: 0117147 Medline TA: Adv Microb Physiol Country: England |
Other Details:
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Languages: eng Pagination: 1-101 Citation Subset: IM |
Affiliation:
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Department of Biology, Indiana University, Bloomington, IN 47405-3700, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Caulobacter crescentus
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cytology,
genetics,
physiology* Cell Cycle / genetics, physiology |
| Grant Support | |
ID/Acronym/Agency:
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F32AI072992/AI/NIAID NIH HHS; GM077648/GM/NIGMS NIH HHS; GM51986/GM/NIGMS NIH HHS; R01 GM051986-14A1/GM/NIGMS NIH HHS; R01 GM077648-02/GM/NIGMS NIH HHS |
| Comments/Corrections | |
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