Document Detail


Complex inheritance: the 21st century.
MedLine Citation:
PMID:  11037340     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
At least for the early years of the twenty-first century we can anticipate some of the advances to be made in mapping, positional cloning, pooling of evidence over samples for linkage and allelic association, and fully parametric methods that combine the latter with segregation analysis. This preoccupation with problems the twentieth century failed to solve is not grounds for pessimism if the new century provides solutions and applies them to problems of biological interest. We may hope that genetic epidemiology will be part of a community that addresses the needs of geneticists for international communication, a stable nomenclature, genome databases, and a consensus on ethical, legal, and social issues transcending regional prejudices.
Authors:
N E Morton
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Advances in genetics     Volume:  42     ISSN:  0065-2660     ISO Abbreviation:  Adv. Genet.     Publication Date:  2001  
Date Detail:
Created Date:  2001-01-17     Completed Date:  2001-02-01     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0370421     Medline TA:  Adv Genet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  535-43     Citation Subset:  IM    
Affiliation:
Human Genetics Research Division, University of Southampton, United Kingdom.
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MeSH Terms
Descriptor/Qualifier:
Chromosome Mapping*
Cloning, Molecular*
Humans
Linkage (Genetics)*
Mathematical Computing

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