Document Detail

Complete right bundle branch block predicts mortality in Thai patients with chronic heart failure with reduced ejection fraction.
MedLine Citation:
PMID:  20462082     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Previous studies have shown that intraventricular conduction defect is associated with increased mortality in heart failure (HF) population. However, it is conflicting whether left bundle branch block (LBBB) or right bundle branch block (RBBB) is a better predictor for mortality. OBJECTIVE: To evaluate the relationship between patterns of bundle branch block (BBB) and all-cause mortality in Thai patients with chronic heart failure with reduced ejection fraction (HFrEF) and to compare the prognostic values of RBBB and LBBB in this population. MATERIAL AND METHOD: The authors retrospectively studied a cohort of 170 patients (age 58 +/- 14 years, male=117) with HFrEF requiring hospitalization and were followed-up in a heart failure clinic. Predictors of mortality were evaluated by Cox proportional hazard analysis. RESULTS: Wide QRS complex (duration >120 ms) was present in 26% of patients, 15% with LBBB, 11% with RBBB. During an average follow-up of 1.8 +/-1.6 years, 22 patients (13%) died. By univariate analysis, presence of chronic renal insufficiency, chronic obstructive pulmonary disease, severe left ventricular systolic dysfunction and RBBB, but not LBBB were associated with increased mortality. After multivariate adjustment, the presence of RBBB was the only strong predictor of mortality in HF patients (OR 3.9, 95% CI 1.3-11.7, p < 0.05). CONCLUSION: The presence of RBBB was the only independent predictor of mortality in Thai patients with HFrEE
Wanwarang Wongcharoen; Arintaya Phrommintikul; Rungsrit Kanjanavanit; Anong Amarittakomol; Paleerat Topaiboon; Warintorn Wiangosot; Srun Kuanprasert; Apichard Sukonthasarn
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  93     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-05-13     Completed Date:  2010-07-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  Thailand    
Other Details:
Languages:  eng     Pagination:  413-9     Citation Subset:  IM    
Department of lnternal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
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MeSH Terms
Asian Continental Ancestry Group*
Bundle-Branch Block / complications,  mortality*,  physiopathology*
Cohort Studies
Heart Failure / complications,  mortality*,  physiopathology*
Middle Aged
Predictive Value of Tests
Retrospective Studies
Risk Factors
Stroke Volume / physiology*

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