| Complete right bundle branch block predicts mortality in Thai patients with chronic heart failure with reduced ejection fraction. | |
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MedLine Citation:
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PMID: 20462082 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Previous studies have shown that intraventricular conduction defect is associated with increased mortality in heart failure (HF) population. However, it is conflicting whether left bundle branch block (LBBB) or right bundle branch block (RBBB) is a better predictor for mortality. OBJECTIVE: To evaluate the relationship between patterns of bundle branch block (BBB) and all-cause mortality in Thai patients with chronic heart failure with reduced ejection fraction (HFrEF) and to compare the prognostic values of RBBB and LBBB in this population. MATERIAL AND METHOD: The authors retrospectively studied a cohort of 170 patients (age 58 +/- 14 years, male=117) with HFrEF requiring hospitalization and were followed-up in a heart failure clinic. Predictors of mortality were evaluated by Cox proportional hazard analysis. RESULTS: Wide QRS complex (duration >120 ms) was present in 26% of patients, 15% with LBBB, 11% with RBBB. During an average follow-up of 1.8 +/-1.6 years, 22 patients (13%) died. By univariate analysis, presence of chronic renal insufficiency, chronic obstructive pulmonary disease, severe left ventricular systolic dysfunction and RBBB, but not LBBB were associated with increased mortality. After multivariate adjustment, the presence of RBBB was the only strong predictor of mortality in HF patients (OR 3.9, 95% CI 1.3-11.7, p < 0.05). CONCLUSION: The presence of RBBB was the only independent predictor of mortality in Thai patients with HFrEE |
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Authors:
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Wanwarang Wongcharoen; Arintaya Phrommintikul; Rungsrit Kanjanavanit; Anong Amarittakomol; Paleerat Topaiboon; Warintorn Wiangosot; Srun Kuanprasert; Apichard Sukonthasarn |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the Medical Association of Thailand = Chotmaihet thangphaet Volume: 93 ISSN: 0125-2208 ISO Abbreviation: J Med Assoc Thai Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-05-13 Completed Date: 2010-07-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7507216 Medline TA: J Med Assoc Thai Country: Thailand |
Other Details:
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Languages: eng Pagination: 413-9 Citation Subset: IM |
Affiliation:
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Department of lnternal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Asian Continental Ancestry Group* Bundle-Branch Block / complications, mortality*, physiopathology* Cohort Studies Female Heart Failure / complications, mortality*, physiopathology* Humans Male Middle Aged Predictive Value of Tests Retrospective Studies Risk Factors Stroke Volume / physiology* Thailand |
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