Document Detail


Complete occlusion of the anterior capsular opening after intact capsulorhexis: clinicopathologic correlation.
MedLine Citation:
PMID:  10088748     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To report histopathologic findings of capsule contraction syndrome with complete occlusion of the capsulorhexis opening. METHODS: Case report. In an 81-year-old woman, a complete occlusion of the anterior capsulorhexis opening developed 2 months after phacoemulsification and intraocular lens implantation. We surgically removed the contracted anterior capsule and analyzed the membrane by standard light microscopy and actin immunohistology. RESULTS: Light microscopic analysis of the membrane showed fibrous tissue subcapsularly with metaplastic lens epithelial cells. The contracted capsulorhexis opening was filled completely with proliferated actin-positive lens epithelial cells. CONCLUSIONS: Complete occlusion of the capsulorhexis opening can be attributed to excessive shrinkage of the capsule, probably caused by actin filaments found in the residual lens epithelial cells together with weak zonular support, and to the occlusion of the remaining central defect by massive proliferation of metaplastic lens epithelial cells.
Authors:
K M Spang; J M Rohrbach; E G Weidle
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of ophthalmology     Volume:  127     ISSN:  0002-9394     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  1999 Mar 
Date Detail:
Created Date:  1999-03-24     Completed Date:  1999-03-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  343-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Ophthalmology, Katharinenhospital Stuttgart, Germany. kspang@compuserve.com
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MeSH Terms
Descriptor/Qualifier:
Actins / metabolism
Aged
Aged, 80 and over
Capsulorhexis / adverse effects*
Cataract / etiology*,  metabolism,  pathology
Cell Division
Epithelial Cells / pathology
Female
Fibrosis
Humans
Immunohistochemistry
Lens Capsule, Crystalline / metabolism,  pathology*
Lens Implantation, Intraocular
Lenses, Intraocular
Phacoemulsification
Polymethyl Methacrylate
Visual Acuity
Chemical
Reg. No./Substance:
0/Actins; 9011-14-7/Polymethyl Methacrylate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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