Document Detail

Complete mole in a dichorionic twin pregnancy after intracytoplasmic sperm injection.
MedLine Citation:
PMID:  23338552     Owner:  NLM     Status:  In-Data-Review    
A dichorionic twin pregnancy with complete hydatidiform mole and coexistent fetus is a rare and challenging situation, whose pathogenesis has not been yet fully understood. We present a case of a 39-year-old woman who underwent intracytoplasmic sperm injection with two embryos transfer. The 12-week gestation ultrasound examination revealed normal fetus and placenta with features of hydatidiform mole, leading to pregnancy termination. Autopsy and histological examinations diagnosed a complete mole coexisting with a normal fetus, and the genetic analysis showed a diploid fetus with biparental genome and molar tissue with paternal diploidy. This case highlighted that complete molar pregnancies may still occur even though pregnancy is achieved after intracytoplasmic sperm injection. A review of the literature was performed by collecting data from the few similar reported cases and by commenting on the pathogenesis of this rare condition.
Tiago José Santos de Matos Ferraz; Carla Maria Magno Bartosch; Carla Maria Almeida Ramalho; Filipa Abreu Gomes de Carvalho; Berta Cecília Campos Lima de Carvalho; Otília Gonçalves Bento Cavaleiro Brandão; Nuno Aires Mota Mendonça Montenegro
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Revista brasileira de ginecologia e obstetrícia : revista da Federação Brasileira das Sociedades de Ginecologia e Obstetrícia     Volume:  35     ISSN:  1806-9339     ISO Abbreviation:  Rev Bras Ginecol Obstet     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214757     Medline TA:  Rev Bras Ginecol Obstet     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  39-43     Citation Subset:  IM    
Serviço de Ginecologia e Obstetrícia, Centro Hospitalar de São João do Porto, Porto, Portugal.
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