Document Detail


Complete mitochondrial sequences for haplogroups M23 and M46: insights into the Asian ancestry of the Malagasy population.
MedLine Citation:
PMID:  20067372     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Through the sequencing of the complete mitochondrial genome of three individuals of Malagasy ancestry, we completed the characterization of the island southeastern Asian specific M46 haplogroup. We assumed that the association of the np 3588 and np 16278 polymorphisms were M46 specific. In addition, we characterized a novel basal M subhaplogroup: M23. This clade can be defined by one coding region transition at np 10295 and one control region transition at np 16263. Our data suggest the arrival of South Asian migrants before the start of the 15th century and highlights the fact that future studies dealing with the settlement of Madagascar should consider at least three potential source populations (Africa, Indonesia, and India).
Authors:
Vincent Dubut; François Cartault; Christine Payet; Marie-Dominique Thionville; Pascal Murail
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Human biology     Volume:  81     ISSN:  1534-6617     ISO Abbreviation:  Hum. Biol.     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2010-01-13     Completed Date:  2010-04-15     Revised Date:  2011-04-18    
Medline Journal Info:
Nlm Unique ID:  0116717     Medline TA:  Hum Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  495-500     Citation Subset:  IM    
Affiliation:
Aix-Marseille Université, CNRS, IRD, UMR 6116-IMEP, Equipe Evolution Génome Environnement, Centre Saint-Charles, Case 36, 3 place Victor Hugo, 13331 Marseille Cedex 3, France.
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MeSH Terms
Descriptor/Qualifier:
Asian Continental Ancestry Group / genetics*
Emigration and Immigration
Evolution, Molecular
Genetic Variation / genetics
Genetics, Population*
Genome, Mitochondrial / genetics*
Haplotypes / genetics
Humans
Madagascar
Phylogeny
Polymorphism, Genetic / genetics
Population Groups / genetics

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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