Document Detail

Complete interruption of the aortic arch in a dog.
MedLine Citation:
PMID:  3693014     Owner:  NLM     Status:  MEDLINE    
Complete interruption of the aortic arch was diagnosed by angiocardiography in a dog with exercise intolerance, a cardiac murmur, polycythemia, and cardiomegaly. The defect was accompanied by a patent ductus arteriosus, ventricular septal defect, and subaortic stenosis. The dog was euthanatized, and the clinical diagnosis was documented by gross dissection of the heart. The site of aortic interruption was between the left carotid and left subclavian arteries, which is the most common location in human beings. The similarity with the pathologic findings of interrupted aortic arch in human beings suggests a similar mechanism responsible for the abnormal cardiac morphogenesis. The defect may be confused with other cardiac anomalies that can result in exercise intolerance, polycythemia, and cardiac murmur. This defect is amenable to surgical treatment, which emphasizes the importance of a correct anatomic diagnosis in clinical patients.
G Jacobs; D Patterson; D Knight
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of the American Veterinary Medical Association     Volume:  191     ISSN:  0003-1488     ISO Abbreviation:  J. Am. Vet. Med. Assoc.     Publication Date:  1987 Dec 
Date Detail:
Created Date:  1988-02-12     Completed Date:  1988-02-12     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7503067     Medline TA:  J Am Vet Med Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1585-8     Citation Subset:  IM    
Department of Small Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens 30602.
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MeSH Terms
Aorta, Thoracic / abnormalities*
Ductus Arteriosus, Patent / pathology,  veterinary
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