Document Detail

Complete hydatidiform mole in a triplet pregnancy coexisting two viable fetuses: case report and review of the literature.
MedLine Citation:
PMID:  14641705     Owner:  NLM     Status:  MEDLINE    
We report a rare case of a complete hydatidiform mole with two or more coexisting fetuses where both infants survived without complications. A male infant weighing 1258 g and a female infant weighing 880 g were delivered without complications and discharged 95 days after the birth. The analysis of DNA microsatellite polymorphisms indicated that the mole was of paternal origin and probably homozygous. The mother suffered from multiple pulmonary metastasis of the hydatidiform mole which was detected 3 days after the surgery and was successfully treated with methotrexate. A complete hydatidiform mole with two or more coexisting fetuses produces a dilemma between immediate termination and pregnancy continuation. Although the present case resulted in a favorable outcome, a review of the 14 reported cases suggests that the high fetal loss rate (90%) must be a consideration in the decision regarding management of such a pregnancy.
Kimiyo Takagi; Nobuya Unno; Hiro-e M Hyodo; Hironobu Hyodo; Hiroyasu Kashima; Noriko Kubota; Yoshihumi Ogiso; Masami Noike; Kazuko Itoh; Shigeki Shiobara; Ikuo Konishi; Shigeru Saito
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The journal of obstetrics and gynaecology research     Volume:  29     ISSN:  1341-8076     ISO Abbreviation:  J. Obstet. Gynaecol. Res.     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2003-12-02     Completed Date:  2004-01-21     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9612761     Medline TA:  J Obstet Gynaecol Res     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  330-8     Citation Subset:  IM    
Department of Obstetrics, Center for Perinatal Medicine, Nagano Children's Hospital, Japan.
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MeSH Terms
Hydatidiform Mole / pathology,  physiopathology*,  ultrasonography
Pregnancy Outcome

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