Document Detail


Complete heart block in a patient with Wegener's granulomatosis in remission--a case report.
MedLine Citation:
PMID:  12025922     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Wegener's granulomatosis is a systemic inflammatory disorder of unknown cause that usually affects the upper and lower respiratory tracts as well as the kidney. Cardiac involvement is rare, although electrocardiographic abnormalities, coronary artery vasculitis, cardiac arrhythmias, and myocardial infarction have been reported in the literature. A 27-year-old female patient with Wegener's granulomatosis in remission is described in whom complete heart block developed in the 13th month of treatment with cyclophosphamide. A temporary pacing was applied and pulse methylprednisolone and cyclophosphamide were commenced. On the ninth day of treatment, normal sinus rhythm was achieved. In conclusion, cardiac rhythm abnormalities should always be kept in mind both in the diagnosis and follow-up of Wegener's granulomatosis.
Authors:
Gultekin Suleymenlar; Metin Sarikaya; Ramazan Sari; Murat Tuncer; Alper Sevinc
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Angiology     Volume:  53     ISSN:  0003-3197     ISO Abbreviation:  Angiology     Publication Date:    2002 May-Jun
Date Detail:
Created Date:  2002-05-23     Completed Date:  2002-06-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  337-40     Citation Subset:  IM    
Affiliation:
Mediterranean University, School of Medicine, Department of Internal Medicine, Antalya, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Adult
Cardiac Pacing, Artificial
Cyclophosphamide / therapeutic use
Female
Heart Block / etiology*,  therapy
Humans
Methylprednisolone / therapeutic use
Wegener Granulomatosis / complications*,  drug therapy
Chemical
Reg. No./Substance:
50-18-0/Cyclophosphamide; 83-43-2/Methylprednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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