Document Detail


Complete heart block in association with graft-versus-host disease.
MedLine Citation:
PMID:  9486500     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An infant who received haploidentical BM for severe combined immunodeficiency (SCID) developed acute, reversible complete heart block in association with an exacerbation of GVHD. Respiratory distress and myocardial dysfunction were also seen with this and previous GVHD exacerbations. The patient had not received chemotherapy or radiation prior to BMT. The complete heart block resolved after 1 week of intensive immunosuppression. The association of complete heart block with GVHD is important because the heart block is potentially reversible with prompt, aggressive control of the GVHD.
Authors:
A L Gilman; N W Kooy; D L Atkins; Z Ballas; S Rumelhart; M Holida; N Lee; F Goldman
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Bone marrow transplantation     Volume:  21     ISSN:  0268-3369     ISO Abbreviation:  Bone Marrow Transplant.     Publication Date:  1998 Jan 
Date Detail:
Created Date:  1998-03-26     Completed Date:  1998-03-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8702459     Medline TA:  Bone Marrow Transplant     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  85-8     Citation Subset:  IM    
Affiliation:
Division of Hematology/Oncology, Department of Pediatrics, University of Iowa College of Medicine, Iowa City, USA.
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MeSH Terms
Descriptor/Qualifier:
Bone Marrow Transplantation / adverse effects*
Graft vs Host Disease / complications*
Heart Block / etiology*
Humans
Immunosuppressive Agents / therapeutic use
Infant
Male
Chemical
Reg. No./Substance:
0/Immunosuppressive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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