Document Detail

Complete heart block and cardiac tamponade secondary to Merkel cell carcinoma cardiac metastases.
MedLine Citation:
PMID:  16466126     Owner:  NLM     Status:  MEDLINE    
This is a unique case of Merkel cell carcinoma, a rare neuroendocrine tumor, metastasizing to the heart and inducing a progression of cardiac complications such as new-onset atrial fibrillation, malignant pericardial effusion with tamponade physiology, first-degree heart block, and complete heart block. Metastases to the heart are relatively rare but should be suspected if a patient with a known neoplasm presents with new cardiac manifestations. This is the first case report of cardiac metastases from Merkel cell carcinoma causing cardiac tamponade or complete heart block. This case highlights the clinical decision-making involved in managing cardiac tamponade and complete heart block in the setting of metastatic disease to the heart.
Maria Conley; Karin Hawkins; David Ririe
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Southern medical journal     Volume:  99     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-02-09     Completed Date:  2006-02-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  74-8     Citation Subset:  AIM; IM    
Department of Internal Medicine, Wilford Hall Medical Center, Lackland Air Force Base, TX 78236, USA.
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MeSH Terms
Carcinoma, Merkel Cell / complications*,  secondary
Cardiac Tamponade / diagnosis,  etiology*
Diagnosis, Differential
Echocardiography, Transesophageal
Fatal Outcome
Follow-Up Studies
Heart Atria / pathology,  radiography,  ultrasonography
Heart Block / diagnosis,  etiology*
Heart Neoplasms / complications*,  secondary
Skin Neoplasms / complications*,  pathology
Tomography, X-Ray Computed
Comment In:
South Med J. 2006 Jan;99(1):4   [PMID:  16466106 ]

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