Document Detail


Complete genome sequence of a novel human parechovirus.
MedLine Citation:
PMID:  23043176     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Human parechoviruses (HPeVs) belonging to the family Picornaviridae are widely spread pathogens among young children. We report the complete genome sequence of a novel HPeV isolated from the stool sample of a hospitalized child with diarrhea in China. The genome consists of 7,305 nucleotides, excluding the 3' poly(A) tail, and has an open reading frame that maps between nucleotide positions 675 and 7217 and encodes a 2,180-amino-acid polyprotein. The genome sequence of the virus was sufficiently distinct from the 8 known HPeV types. Phylogenetic analysis based on the complete genome indicated that the HPeV strain represents a new genotype.
Authors:
Chunmei Wang; Tongling Shan; Hao Zheng; Wu Tong; Fangzhou Chen; Han Hu; Qigai He; Guangzhi Tong
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of virology     Volume:  86     ISSN:  1098-5514     ISO Abbreviation:  J. Virol.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-10-08     Completed Date:  2013-01-07     Revised Date:  2013-07-11    
Medline Journal Info:
Nlm Unique ID:  0113724     Medline TA:  J Virol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  11945-6     Citation Subset:  IM    
Affiliation:
State Key Laboratory of Agricultural Microbiology, Division of Animal Infectious Disease, Huazhong Agricultural University, Wuhan, Hubei, China.
Data Bank Information
Bank Name/Acc. No.:
GENBANK/JX441355
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MeSH Terms
Descriptor/Qualifier:
Child, Hospitalized
Child, Preschool
China
Cluster Analysis
Diarrhea / virology
Feces / virology
Genome, Viral*
Humans
Molecular Sequence Data
Open Reading Frames
Parechovirus / classification,  genetics*,  isolation & purification
Phylogeny
Picornaviridae Infections / virology
Polyproteins / genetics
RNA, Viral / genetics*
Sequence Analysis, DNA*
Viral Proteins / genetics
Chemical
Reg. No./Substance:
0/Polyproteins; 0/RNA, Viral; 0/Viral Proteins
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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