Document Detail

Complete genome sequence of Le Blanc virus, a third Caenorhabditis nematode-infecting virus.
MedLine Citation:
PMID:  23043172     Owner:  NLM     Status:  MEDLINE    
Orsay virus and Santeuil virus, the first known viruses capable of naturally infecting the nematodes Caenorhabditis elegans and Caenorhabditis briggsae, respectively, were recently identified by high-throughput sequencing of wild Caenorhabditis strains. By similar analysis of another wild C. briggsae isolate, we have now discovered and sequenced the complete genome of a third novel virus, Le Blanc virus, that is distantly related to Orsay and Santeuil viruses. All three viruses are positive-sense RNA viruses with bipartite genomes that are most closely related to nodaviruses. Identification of a third virus capable of infecting Caenorhabditis nematodes enables comparative analysis of this clade of viruses and strengthens this model for investigating virus-host interactions.
Carl J Franz; Guoyan Zhao; Marie-Anne Félix; David Wang
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of virology     Volume:  86     ISSN:  1098-5514     ISO Abbreviation:  J. Virol.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-10-08     Completed Date:  2013-01-07     Revised Date:  2013-07-11    
Medline Journal Info:
Nlm Unique ID:  0113724     Medline TA:  J Virol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  11940     Citation Subset:  IM    
Departments of Molecular Microbiology and Pathology & Immunology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Data Bank Information
Bank Name/Acc. No.:
GENBANK/JQ943579;  JQ943580
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MeSH Terms
Caenorhabditis / virology
Cluster Analysis
Genome, Viral*
Molecular Sequence Data
RNA Viruses / classification,  genetics*,  isolation & purification
RNA, Viral / genetics*
Sequence Analysis, DNA*
Reg. No./Substance:
0/RNA, Viral

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