Document Detail


Complete genome sequence of a J subgroup avian leukosis virus isolated from local commercial broilers.
MedLine Citation:
PMID:  23043170     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Subgroup J avian leukosis virus (ALV-J) isolate GDKP1202 was isolated from a 50-day-old local yellow commercial broiler in the Guangdong province of China in 2012. Here we report the complete genomic sequence of the GDKP1202 isolate, which caused high mortality, serious growth suppression, thymic atrophy, and liver enlargement in commercial broilers. A novel potential binding site (5'-GGCACCTCC-3') for c-myb was identified in the GDKP1202 genome. These findings will provide additional insights into the molecular characteristics in the genomes and pathogenicity of ALV-J.
Authors:
Hongxin Li; Chunyi Xue; Jun Ji; Shuang Chang; Huiqin Shang; Lingjun Zhang; Jingyun Ma; Yingzuo Bi; Qingmei Xie
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of virology     Volume:  86     ISSN:  1098-5514     ISO Abbreviation:  J. Virol.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-10-08     Completed Date:  2013-01-07     Revised Date:  2013-07-11    
Medline Journal Info:
Nlm Unique ID:  0113724     Medline TA:  J Virol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  11937-8     Citation Subset:  IM    
Affiliation:
College of Animal Science, South China Agricultural University, Guangzhou, China.
Data Bank Information
Bank Name/Acc. No.:
GENBANK/JX453210
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MeSH Terms
Descriptor/Qualifier:
Animals
Avian Leukosis / mortality,  pathology,  virology
Avian leukosis virus / genetics*,  isolation & purification,  pathogenicity
Binding Sites
Chickens
China
Genome, Viral*
Molecular Sequence Data
Protein Binding
Proto-Oncogene Proteins c-myb / metabolism
RNA, Viral / genetics*
Sequence Analysis, DNA*
Chemical
Reg. No./Substance:
0/Proto-Oncogene Proteins c-myb; 0/RNA, Viral
Comments/Corrections

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