| Complete genome sequence analysis of a natural reassortant infectious bursal disease virus in China. | |
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MedLine Citation:
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PMID: 23043174 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A novel isolate of infectious bursal disease virus (IBDV) was designated GX-NN-L. The GX-NN-L IBDV was a very virulent infectious bursal disease virus (vvIBDV) isolated from broiler flocks in Guangxi province, China, in 2011. The GX-NN-L IBDV caused high mortality, immunosuppression, low weight gain, and bursal atrophy in commercial broilers. Here, we report the complete genome sequence of the GX-NN-L IBDV, a reassortment strain with segments A and B derived from very virulent strains and attenuated IBDV, respectively. These findings from this study provide additional insights into the genetic exchange between attenuated and very virulent strains of IBDV and continuous monitoring of the spread of the virus in chicken. |
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Authors:
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Feng Chen; Jiajia Liu; Zhuanqiang Yan; Di Liu; Jun Ji; Jianping Qin; Haiyan Li; Jingyun Ma; Yingzuo Bi; Qingmei Xie |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of virology Volume: 86 ISSN: 1098-5514 ISO Abbreviation: J. Virol. Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-10-08 Completed Date: 2013-01-07 Revised Date: 2013-05-20 |
Medline Journal Info:
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Nlm Unique ID: 0113724 Medline TA: J Virol Country: United States |
Other Details:
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Languages: eng Pagination: 11942-3 Citation Subset: IM |
Affiliation:
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College of Animal Science, South China Agricultural University, Tianhe District, Guangzhou, Guangdong, People's Republic of China. |
| Data Bank Information | |
Bank Name/Acc. No.:
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GENBANK/JX134485; JX134486 |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Atrophy / pathology Birnaviridae Infections / mortality, veterinary, virology Body Weight Bursa of Fabricius / pathology Chickens China Genome, Viral* Immune Tolerance Infectious bursal disease virus / genetics*, isolation & purification, pathogenicity Molecular Sequence Data Poultry Diseases / mortality, virology RNA, Viral / genetics* Reassortant Viruses / genetics*, isolation & purification, pathogenicity Sequence Analysis, DNA* Survival Analysis |
| Chemical | |
Reg. No./Substance:
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0/RNA, Viral |
| Comments/Corrections | |
Erratum In:
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J Virol. 2013 Feb;87(4):2373 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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