| Complete clinical remission and subsequent relapse of bronchiectasis-related (AA) amyloid induced nephrotic syndrome. | |
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MedLine Citation:
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PMID: 8938683 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Systemic amyloidosis normally has a dismal prognosis. However, there are several case reports of protracted survival, usually as a response to measures designed to retard the further deposition of amyloid fibrils. In AA amyloid, most commonly associated with inflammatory rheumatological, bowel, and chest diseases, such interventions have had some success, but the dramatic response of complete resolution of nephrotic syndrome as a result of the regular institution of postural chest drainage and antibiotic therapy, in the clinical context of bronchiectasis, has been previously reported only once. In both of our cases, after protracted remission, such therapy was abandoned by the patients, leading both to recurrence of nephrotic syndrome and also eventually to end-stage renal failure requiring dialysis. |
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Authors:
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D J Goldsmith; I S Roberts; C D Short; N P Mallick |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Nephron Volume: 74 ISSN: 0028-2766 ISO Abbreviation: Nephron Publication Date: 1996 |
Date Detail:
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Created Date: 1997-02-20 Completed Date: 1997-02-20 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0331777 Medline TA: Nephron Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 572-6 Citation Subset: IM |
Affiliation:
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Renal Unit, Royal Infirmary, Manchester, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Amyloidosis / complications, pathology*, therapy Bronchiectasis / complications, pathology*, therapy Female Humans Male Middle Aged Nephrotic Syndrome / complications, pathology*, therapy Recurrence Remission Induction Serum Amyloid A Protein / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Serum Amyloid A Protein |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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