| Complete blood cell count and retinal vessel diameters. | |
| | |
MedLine Citation:
|
PMID: 21482874 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To examine the cross-sectional associations of components of the complete blood cell count with retinal vessel diameters. METHODS: The data are from the baseline examination of the Beaver Dam Eye Study cohort (n = 4730) from March 1, 1988, to September 14, 1990. Blood pressure was measured, a medical history including questions on cigarette smoking was obtained, and fundus photographs centered on the optic disc were taken and digitized. Retinal arteriole and venule diameters were measured using computer-assisted software. The central retinal arteriole equivalent and central retinal venule equivalent were computed. A complete blood cell count was done. RESULTS: In age- and sex-adjusted analyses, red blood cell count, hemoglobin level, hematocrit, and white blood cell count were all statistically significantly associated with central retinal venule equivalent and central retinal arteriole equivalent, while platelet count was associated only with central retinal venule equivalent. These relationships persisted in more fully adjusted models, except platelet count became statistically significantly associated with both central retinal arteriole equivalent and central retinal venule equivalent. CONCLUSIONS: Blood components as measured in a complete blood cell count are significant correlates of retinal vessel diameters and should be considered in analyses where retinal blood vessel diameters are outcomes. |
| | |
Authors:
|
Barbara E K Klein; Ronald Klein; Chelsea E Myers; Kristine E Lee |
Related Documents
:
|
6830844 - Chemical and immunological identification of glycolipid-based blood group abh and lewis... 21784084 - Distance between laser head and skin does not influence skin blood flow values recorded... 22032634 - Hierarchical analysis of anaemia deferral in blood donor candidates: the individual in ... 2652934 - Abo blood grouping of hairs using an avidin-biotin-peroxidase complex technique. 3117164 - Reduced response of cerebral blood flow to hypercapnia: restoration by extracranial-int... 19867824 - Studies on the chemistry of serous effusions. |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Archives of ophthalmology Volume: 129 ISSN: 1538-3601 ISO Abbreviation: Arch. Ophthalmol. Publication Date: 2011 Apr |
Date Detail:
|
Created Date: 2011-04-12 Completed Date: 2011-06-10 Revised Date: 2012-04-04 |
Medline Journal Info:
|
Nlm Unique ID: 7706534 Medline TA: Arch Ophthalmol Country: United States |
Other Details:
|
Languages: eng Pagination: 490-7 Citation Subset: AIM; IM |
Affiliation:
|
Department of Ophthalmology and Visual Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, 610 N Walnut Street, Madison, WI 53726-2336, USA. kleinb@epi.ophth.wisc.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Aged, 80 and over Arterioles / anatomy & histology Blood Cell Count* Blood Pressure / physiology Cross-Sectional Studies Female Hematocrit Hemoglobin A, Glycosylated / physiology Humans Image Processing, Computer-Assisted Male Middle Aged Photography Retinal Vessels / anatomy & histology* Venules / anatomy & histology Wisconsin / epidemiology |
| Grant Support | |
ID/Acronym/Agency:
|
EY06594/EY/NEI NIH HHS; U10 EY006594-24/EY/NEI NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Hemoglobin A, Glycosylated |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Vitamin D status and early age-related macular degeneration in postmenopausal women.
Next Document: Fred loe, MD, and the history of trachoma.