Document Detail


Complementary feeding: clinically relevant factors affecting timing and composition.
MedLine Citation:
PMID:  17284770     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Exclusive breastfeeding for the first 6 mo of life followed by optimal complementary feeding are critical public health measures for reducing and preventing morbidity and mortality in young children. Clinical factors, such as birth weight, prematurity, and illness, that affect the iron and zinc requirements of younger infants are discussed. Maternal diet and nutritional status do not have a strong effect on the mineral content of human milk, but physiologic changes in milk and the infants' status determine the dependence of the infant on complementary foods in addition to human milk to meet iron and zinc requirements after 6 mo. The nature of zinc absorption, which is suitably characterized by saturation response modeling, dictates that plant-based diets, which are low in zinc, are associated with low absolute daily absorbed zinc, which is inadequate to meet requirements. Foods with a higher zinc content, such as meats, are much more likely to be sufficient to meet dietary requirements. Current plant-based complementary feeding patterns for older fully breastfed infants in both developed and developing countries pose a risk of zinc deficiency. The strong rationale for the potential benefits of providing meat as an early complementary food, and the examples of successful intervention programs, provide potent incentives to pursue broader implementation programs, with concurrent rigorous evaluation of both efficacy and effectiveness.
Authors:
Nancy F Krebs; K Michael Hambidge
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  85     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-02-07     Completed Date:  2007-03-13     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  639S-645S     Citation Subset:  AIM; IM    
Affiliation:
Section of Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Denver, CO 80252, USA. nancy.krebs@uchsc.edu
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MeSH Terms
Descriptor/Qualifier:
Anemia, Iron-Deficiency
Breast Feeding*
Female
Homeostasis
Humans
Infant
Infant, Newborn
Iron
Maternal Nutritional Physiological Phenomena*
Micronutrients
Nutritional Requirements
Time Factors
Zinc / metabolism
Grant Support
ID/Acronym/Agency:
HD04024/HD/NICHD NIH HHS; K24 RR018357-01/RR/NCRR NIH HHS; RR00069/RR/NCRR NIH HHS; U01 HD40657/HD/NICHD NIH HHS
Chemical
Reg. No./Substance:
0/Micronutrients; 7439-89-6/Iron; 7440-66-6/Zinc

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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