| Complement consumption and progression to post-streptococcal nephrotic syndrome. A report of two cases. | |
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MedLine Citation:
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PMID: 705557 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The immunopathogenesis of the nephrotic syndrome which occurs in about 0,3% of Black children with post-streptococcal glomerulonephritis has not been clearly defined. Findings in 2 out of 582 Black children with post-streptococcal glomerulonephritis who developed nephrotic syndrome suggest that minimal activation in the blood of complement components, particularly C3, early in the nephritic process may determine progression to nephrosis. Differences reported by other workers between normocomplementaemic and hypocomplementaemic patients with post-streptococcal glomerulonephritis support this interpretation. |
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Authors:
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R Diedericks; H M Coovadia |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde Volume: 54 ISSN: 0256-9574 ISO Abbreviation: S. Afr. Med. J. Publication Date: 1978 Jul |
Date Detail:
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Created Date: 1978-12-27 Completed Date: 1978-12-27 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0404520 Medline TA: S Afr Med J Country: SOUTH AFRICA |
Other Details:
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Languages: eng Pagination: 208-10 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Child Complement C3 / metabolism* Complement System Proteins / metabolism Female Glomerulonephritis / complications Humans Male Nephrotic Syndrome / etiology*, immunology Streptococcal Infections* |
| Chemical | |
Reg. No./Substance:
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0/Complement C3; 9007-36-7/Complement System Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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