Document Detail

Complement activity and selected hematologic variables in newborn foals fed bovine colostrum.
MedLine Citation:
PMID:  2802328     Owner:  NLM     Status:  MEDLINE    
Serum complement activity and selected hematologic variables were evaluated in 5 newborn foals fed bovine colostrum (principal group) and 6 foals allowed to nurse their dam (control group). Also, bovine colostrum was evaluated for anti-equine antibodies. Precolostral serum hemolytic and conglutinating complement activities were low and increased similarly in foals of both groups to reach adult values between 1 and 3 weeks after birth. Bovine colostrum strongly agglutinated, but did not hemolyse principal foals' RBC and blood containing all known equine blood group alloantigens. Hemolysis was not detected after administration of bovine colostrum. Physiologic anemia developed in foals of principal and control groups during the first week of life. Erythrocyte osmotic fragility in foals of the principal group prior to and after the ingestion of colostrum remained unchanged. However, at 36 hours after birth, there was a significant decrease in erythrocyte osmotic fragility in foals fed homologous colostrum.
J P Lavoie; M S Spensley; B P Smith; A T Bowling; S Morse
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of veterinary research     Volume:  50     ISSN:  0002-9645     ISO Abbreviation:  Am. J. Vet. Res.     Publication Date:  1989 Sep 
Date Detail:
Created Date:  1989-11-06     Completed Date:  1989-11-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375011     Medline TA:  Am J Vet Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1532-6     Citation Subset:  IM    
Department of Medicine, School of Veterinary Medicine, University of California, Davis 95616.
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MeSH Terms
Animals, Newborn / blood,  immunology*
Blood Proteins / analysis
Colostrum / immunology*
Complement Hemolytic Activity Assay
Complement System Proteins / analysis*
Horses / blood,  immunology*
Osmotic Fragility
Reg. No./Substance:
0/Blood Proteins; 9007-36-7/Complement System Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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