Document Detail

Compiled data on aminoglycoside, foremost netilmicin susceptibility of bacterial strains.
MedLine Citation:
PMID:  6782657     Owner:  NLM     Status:  MEDLINE    
The MIC-values of 73 bacterial strains isolated in Malmö from patients treated with netilmicin have been determined by the agar dilution method for five aminoglycosides: amikacin, gentamicin, netilmicin, sisomicin and tobramycin. The results are compared with those obtained with the disc diffusion method in another Swedish investigation, comprising 202 strains and with results obtained in other places. Among the strains isolated in the two Swedish investigations, Escherichia coli strains were most prevalent, 28 and 77 respectively, and in this group no important differences could be found except for sisomicin. The importance of the inoculum size was investigated in a separate study on 24 strains of the Malmö material. These strains had also been tested one year earlier, using another size of the inoculum. The comparison showed that an inoculum less than 10(4) colony forming units resulted in lower MIC-values.
I Juhlin; G Tunevall
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Scandinavian journal of infectious diseases. Supplementum     Volume:  Suppl 23     ISSN:  0300-8878     ISO Abbreviation:  Scand J Infect Dis Suppl     Publication Date:  1980  
Date Detail:
Created Date:  1981-05-13     Completed Date:  1981-05-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0251025     Medline TA:  Scand J Infect Dis Suppl     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  39-44     Citation Subset:  IM    
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MeSH Terms
Acinetobacter / drug effects
Amikacin / pharmacology*
Anti-Bacterial Agents / pharmacology*
Bacteria / drug effects*
Escherichia coli / drug effects
Gentamicins / pharmacology*
Kanamycin / analogs & derivatives*
Microbial Sensitivity Tests
Netilmicin / pharmacology*
Pseudomonas aeruginosa / drug effects
Staphylococcus aureus / drug effects
Tobramycin / pharmacology*
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Gentamicins; 32986-56-4/Tobramycin; 37517-28-5/Amikacin; 56391-56-1/Netilmicin; 59-01-8/Kanamycin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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