Document Detail


Compilation of eukaryotic sequences around transcription initiation sites.
MedLine Citation:
PMID:  3795990     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
All vertebrate and invertebrate sequences present in the GenBank database have been aligned according to their mRNA start sites. For some cases the regions between positions -110 and +110 are presented. Previously, two general transcription initiation signals have been noted, the universal TATA box at position -30 and the CAAT box at -75. Our analysis indicates the presence of other signals, at least as significant as the CAAT. Inspection of the aligned sequences reveals the high concentration of G + C near mRNA initiation sites in non-mammalian vertebrates and in mammalians.
Authors:
R Nussinov
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of theoretical biology     Volume:  120     ISSN:  0022-5193     ISO Abbreviation:  J. Theor. Biol.     Publication Date:  1986 Jun 
Date Detail:
Created Date:  1987-01-23     Completed Date:  1987-01-23     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0376342     Medline TA:  J Theor Biol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  479-87     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Base Sequence
Invertebrates
Mammals
RNA, Messenger / genetics
Transcription, Genetic*
Chemical
Reg. No./Substance:
0/RNA, Messenger

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Cell cycle controls in higher eukaryotic cells: resting state or a prolonged G1 period?
Next Document:  Parasite immunology and lymphocyte population dynamics.