| Compensatory enlargement of a solitary functioning kidney during fetal development. | |
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MedLine Citation:
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PMID: 22581658 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: To determine the time of onset and degree of compensatory enlargement of the fetal solitary kidney in fetuses with unilateral renal agenesis (URA) or unilateral multicystic kidney dysplasia (MCKD). METHODS: Of 67 fetuses, 60 MCDK and 7 URA and no other congenital anomalies, a total of 147 kidney length measurements were obtained retrospectively in our prenatal ultrasound database. A nomogram was established and compared to nomograms of normal kidney length. RESULTS: Compensatory enlargement, defined as renal length >95(th) percentile for gestational age was demonstrated in 87% and 100% of the MCKD and URA cases respectively, leading to a total of 88%. In the 38(th) week of gestation the mean enlargement, defined as mean renal length of a SFK >50(th) percentile for normal renal length, was 22.2% (9.61 mm) and the mean compensatory enlargement, defined as mean renal length of a SFK >95(th) percentile for normal renal length, was 11.3% (5.25 mm). Compensatory growth of solitary kidneys is demonstrated from the 20(th) week of gestation and onward. CONCLUSION: This study demonstrates compensatory enlargement of a SFK from the 20(th) week of gestation and onward, occurs in 88% of the fetuses and has a mean enlargement of 11.3% by the 37(th) week of gestation. Copyright © 2012 ISUOG. Published by John Wiley & Sons, Ltd. |
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Authors:
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S H van Vuuren; R van der Doef; T E Cohen-Overbeek; R Goldschmeding; L R Pistorius; T P V M de Jong |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-5-14 |
Journal Detail:
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Title: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology Volume: - ISSN: 1469-0705 ISO Abbreviation: - Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-5-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9108340 Medline TA: Ultrasound Obstet Gynecol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 ISUOG. Published by John Wiley & Sons, Ltd. |
Affiliation:
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Department of Pathology, University Medical Centre Utrecht, Rotterdam, The Netherlands. S.H.vanvuuren@umcutrecht.nl. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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