| Comparison of yogurt, soybean, casein, and amino acid-based diets in children with persistent diarrhea. | |
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MedLine Citation:
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PMID: 19700033 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Although previous studies have shown successful treatment of persistent diarrhea (PD) with the use of yogurt-based diets, some recent ones speculate the need of special formulas for the nutritional management of PD complicated cases. In the present study, we tested the hypothesis that the consumption of 3 lactose-free diets, with different degrees of complexity, is associated with lower stool output and shorter duration of diarrhea when compared with the use of a yogurt-based one on the nutritional management of PD. A total of 154 male infants, aged between 1 and 30 months, with PD and with or without dehydration, were randomly assigned to 1 of 4 treatment groups. Throughout the study, the patients were placed in a metabolic unit; their body weights and intakes of oral rehydration solution, water, and formula diets, in addition to outputs of stool, urine, and vomit, were measured and recorded at 24-hour intervals. Four different diets were used in this study: diet 1, yogurt-based formula; diet 2, soy-based formula; diet 3, hydrolyzed protein-based formula; and diet 4, amino acid-based formula. Throughout the study, only these formula diets were fed to the children. The data showed that children fed the yogurt-based diet (diet 1) or the amino acid-based diet (diet 4) had a significant reduction in stool output and in the duration of diarrhea. The use of an inexpensive and worldwide-available yogurt-based diet is recommended as the first choice for the nutritional management of mild to moderate PD. For the few complicated PD cases, when available, a more complex amino acid-based diet should be reserved for the nutritional management of these unresponsive and severe presentations. Soy-based or casein-based diets do not offer any specific advantage or benefits and do not seem to have a place in the management of PD. |
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Authors:
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Angela P de Mattos; Tereza C M Ribeiro; Patrícia S A Mendes; Sandra S Valois; Carlos M C Mendes; Hugo C Ribeiro |
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Publication Detail:
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Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Nutrition research (New York, N.Y.) Volume: 29 ISSN: 1879-0739 ISO Abbreviation: - Publication Date: 2009 Jul |
Date Detail:
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Created Date: 2009-08-24 Completed Date: 2009-10-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8303331 Medline TA: Nutr Res Country: United States |
Other Details:
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Languages: eng Pagination: 462-9 Citation Subset: IM |
Affiliation:
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Fima Lifshitz Research Center, Pediatric Hospital, Federal University of Bahia, Bahia, Brazil. mattosangela@gmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acids
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pharmacology,
therapeutic use* Caseins / pharmacology, therapeutic use* Defecation / drug effects* Diarrhea / diet therapy* Dietary Proteins / pharmacology, therapeutic use* Humans Hydrolysis Infant Lactose Male Soybean Proteins / pharmacology, therapeutic use* Time Factors Yogurt* |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 0/Caseins; 0/Dietary Proteins; 0/Soybean Proteins; 63-42-3/Lactose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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