Document Detail

Comparison of ventricular long-axis function in patients with cardiac amyloidosis versus idiopathic restrictive cardiomyopathy.
MedLine Citation:
PMID:  15619416     Owner:  NLM     Status:  MEDLINE    
To investigate ventricular long-axis function in cardiac amyloidosis (CA) and idiopathic restrictive cardiomyopathy (IRC), 16 patients with CA and 14 with IRC were studied. Left ventricular (LV) long-axis function was depressed in all patients with CA compared with only 36% of patients with IRC. Impairment in longitudinal function was clearly evident, even if fractional shortening and LV filling were normal. Ventricular long-axis function may be used as a sensitive marker of early systolic dysfunction. CA and IRC have quite distinct pathophysiologic profiles, raising some concerns about the appropriateness of considering them as 2 subtypes of a single nosographic entity.
Enrica Perugini; Claudio Rapezzi; Letizia Bacchi Reggiani; Philip Poole-Wilson; Angelo Branzi; Michael Y Henein
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  95     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2004-12-27     Completed Date:  2005-02-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  146-9     Citation Subset:  AIM; IM    
The Royal Brompton Hospital, London, United Kingdom. <>
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MeSH Terms
Amyloidosis / complications,  physiopathology*
Cardiomyopathies / complications,  physiopathology*
Cardiomyopathy, Restrictive / physiopathology
Ventricular Function, Left*

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