Document Detail


Comparison of various imaging methods with particular evaluation of color Doppler sonography for planning surgery for breast tumors.
MedLine Citation:
PMID:  10326635     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Color Doppler sonography (CD) was compared with other diagnostic imaging methods [mammography (MG), breast ultrasound (US) and magnetic resonance imaging (MRI)] in the planning of surgery for breast tumors. MATERIALS AND METHODS: 99 patients with breast cancer and 101 with ultimately benign breast lesions were examined preoperatively. The specificity and sensitivity were calculated, as well as the predictive values. Various qualitative and semiquantitative CD parameters were also analysed for their diagnostic value. RESULTS: The sensitivity/specificity of the various methods (in %) was: MG 85/77; US 95/80; CD 82/75; MRI 90/63. The positive predictive value (ppv)/negative predictive value (npv) (in %) was: MG 79/83; US 81/94; CD 72/84; MRI 79/63. The median maximum systolic flow velocity and the resistance index (RI) were significantly higher in breast cancer vessels than in benign lesions. The number of pulsating color pixels detected by CD was significantly higher for breast cancer. In cases of breast cancer significantly more blood flows were detected in the body of the tumor than at its periphery. CONCLUSION: Color Doppler sonography was not superior to other diagnostic methods for preoperative assessment of a breast lesion. The combination of all diagnostic procedures gave a correct classification rate of 93.3% and is much better than the correct classification of any single diagnostic imaging procedure.
Authors:
J U Blohmer; H Oellinger; C Schmidt; P Hufnagl; R Felix; W Lichtenegger
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  262     ISSN:  0932-0067     ISO Abbreviation:  Arch. Gynecol. Obstet.     Publication Date:  1999  
Date Detail:
Created Date:  1999-07-13     Completed Date:  1999-07-13     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  159-71     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Medizinische Fakultät, Humboldt-Universität Berlin.
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MeSH Terms
Descriptor/Qualifier:
Aged
Biopsy
Blood Flow Velocity / physiology
Breast Neoplasms / blood supply,  diagnosis*,  radiography,  ultrasonography*
Carcinoma / blood supply,  diagnosis*,  radiography,  ultrasonography*
Diagnosis, Differential
Discriminant Analysis
Evaluation Studies as Topic
Female
Humans
Magnetic Resonance Imaging
Mammography
Middle Aged
Predictive Value of Tests
Preoperative Care
Prospective Studies
Sensitivity and Specificity
Ultrasonography, Doppler, Color*
Vascular Resistance / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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