| Comparison of two radionuclide techniques for detecting disease of right and left coronary arteries. | |
| | |
MedLine Citation:
|
PMID: 7250889 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Radionuclide angiography and thallium-201 myocardial perfusion scintigraphy were compared in 31 patients with coronary artery disease studied at rest and during exercise. Seventeen of the 31 patients had perfusion defects on thallium-201 redistribution scans (61%); 16 of these had prior transmural infarction. Six other patients with prior inferior infarction had no defects on thallium-201 redistribution scans. During treadmill exercise, 28 of 31 patients (90%) developed new or larger thallium-201 perfusion defects, a significantly higher percentage of patients than those that developed ST segment abnormalities during exercise (74%). During bicycle exercise left ventricular ejection fraction decreased in 27 of the 31 patients (87%); the average change in left ventricular ejection fraction was from 54 +/- 16+ to 48 +/- 14% (p less than 0.1). Twenty-three of the 31 patients had abnormalities of regional ejection fraction at rest (74%), while 30 of the 31 had abnormalities during exercise (97%). The number of patients who developed new regional ejection fraction abnormalities during exercise (28 of 31) was not significantly different from the number of patients who developed new or larger thallium-201 myocardial perfusion defects during exercise. In order to compare the two radionuclide techniques with respect to identification of vessel involvement, the patients were separated into those with disease of the right coronary system, disease of the left coronary system, or both. Thallium-201 scintigraphy correctly identified ten of 14 patients with involvement of only the right or left system; radionuclide angiography correctly identified six of 14. However, radionuclide angiography identified more patients with right and left system involvement (15/17) than did thallium-201 scintigraphy (6/17), p less than .01. These data suggest radionuclide angiography is more useful for identifying patients with disease of both the right and left coronary arteries. |
| | |
Authors:
|
L L Johnson; C F Cabot; D M McCarthy; R R Sciacca; B R Rudin; D K Blood; P J Cannon |
Related Documents
:
|
22562499 - Impaired global myocardial flow dynamics despite normal left ventricular function and r... 2392049 - Echo planar imaging of isolated perfused rat hearts at 4.7 t: a comparison of langendor... 17446789 - Contrast ultrasound in the assessment of patients presenting with suspected cardiac isc... 15077089 - Relationship of myocardial perfusion imaging findings to outcome of patients with heart... 18562719 - Quantification of myocardial perfusion by contrast-enhanced 64-mdct: characterization o... 7826309 - Myocardial perfusion measured by dual-isotope acquisition of 81rubidium/81mkrypton: an ... 1985319 - Assessment of stable ischemic heart disease. which tests are best for which patients? 1396859 - Coronary haemodynamics in hypertensive heart disease. 8305279 - Cardiac effects of coronary arteriography with electrolyte addition to iohexol. a study... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Herz Volume: 6 ISSN: 0340-9937 ISO Abbreviation: Herz Publication Date: 1981 Jun |
Date Detail:
|
Created Date: 1981-09-15 Completed Date: 1981-09-15 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 7801231 Medline TA: Herz Country: GERMANY, WEST |
Other Details:
|
Languages: eng Pagination: 166-77 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Angina Pectoris / radionuclide imaging Computers Coronary Circulation Coronary Disease / radionuclide imaging* Coronary Vessels / radionuclide imaging Female Hemodynamics Humans Male Middle Aged Myocardial Contraction Physical Exertion Radioisotopes / diagnostic use Thallium / diagnostic use |
| Grant Support | |
ID/Acronym/Agency:
|
HL-14148/HL/NHLBI NIH HHS; HL-21006/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Radioisotopes; 7440-28-0/Thallium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Left atrial function in acute mitral regurgitation. Factors which modify the regurgitant volume.
Next Document: Left ventricular dimensions and systolic function during spontaneous heart rate changes: an echocard...