Document Detail


Comparison of two different methods for the evaluation of left ventricular ejection fraction in patients with coronary artery disease.
MedLine Citation:
PMID:  12463623     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The evaluation of left ventricular ejection fraction (LVEF) may be troublesome in difficult clinical settings in patients with coronary artery disease (CAD). The aim of this study was to compare 2 simple geometrical and nongeometrical methods of LVEF evaluation that could overcome the typical technical limitations of ultrasound examination. The authors studied 26 patients with proven CAD (63+/-10 years) who underwent left ventricular (LV) catheterization and coronary angiography during the hospital stay. A complete 2D-Doppler echocardiography was performed and LVEF was evaluated with the formula by Wyatt (W-LVEF), which relates the left ventricle to a biplane ellipsoidal figure, and by the myocardial performance index (MPI) formula (MPI-LVEF), MPI being an index of systodiastolic function. Mean MPI-LVEF was 41+/-8% and was significantly lower with respect to contrast angiography (52+/-14%, p = 0.0003) and to W-LVEF (49+/-13%, p = 0.0009). There was no statistically significant correlation between MPI-LVEF and geometric (either angiographic or ultrasound) LVEF. Bland-Altman analysis showed lack of agreement between MPI-LVEF and any other method evaluated in the study. MPI-LVEF may not be reliable and accurate for the evaluation of systolic function in patients with CAD. Nonetheless, the evaluation of global LV function by means of MPI may represent a valuable and affordable alternative to expensive and time-consuming methods, especially in the presence of difficult technical settings.
Authors:
Daniele Pontillo; Nicolino Patruno; Aldo Capezzuto; Francesco Serra; Massimo Sassara; Enrico Vittorio Scabbia
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Angiology     Volume:  53     ISSN:  0003-3197     ISO Abbreviation:  Angiology     Publication Date:    2002 Nov-Dec
Date Detail:
Created Date:  2002-12-04     Completed Date:  2002-12-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  693-8     Citation Subset:  IM    
Affiliation:
Division of Cardiology, Belcolle Hospital, Viterbo, Italy. dpontillo@libero.it
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MeSH Terms
Descriptor/Qualifier:
Coronary Angiography*
Coronary Disease / physiopathology*
Echocardiography, Doppler*
Female
Heart Catheterization
Humans
Linear Models
Male
Middle Aged
Stroke Volume / physiology
Ventricular Function, Left / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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