Document Detail

Comparison of two different methods for the evaluation of left ventricular ejection fraction in patients with coronary artery disease.
MedLine Citation:
PMID:  12463623     Owner:  NLM     Status:  MEDLINE    
The evaluation of left ventricular ejection fraction (LVEF) may be troublesome in difficult clinical settings in patients with coronary artery disease (CAD). The aim of this study was to compare 2 simple geometrical and nongeometrical methods of LVEF evaluation that could overcome the typical technical limitations of ultrasound examination. The authors studied 26 patients with proven CAD (63+/-10 years) who underwent left ventricular (LV) catheterization and coronary angiography during the hospital stay. A complete 2D-Doppler echocardiography was performed and LVEF was evaluated with the formula by Wyatt (W-LVEF), which relates the left ventricle to a biplane ellipsoidal figure, and by the myocardial performance index (MPI) formula (MPI-LVEF), MPI being an index of systodiastolic function. Mean MPI-LVEF was 41+/-8% and was significantly lower with respect to contrast angiography (52+/-14%, p = 0.0003) and to W-LVEF (49+/-13%, p = 0.0009). There was no statistically significant correlation between MPI-LVEF and geometric (either angiographic or ultrasound) LVEF. Bland-Altman analysis showed lack of agreement between MPI-LVEF and any other method evaluated in the study. MPI-LVEF may not be reliable and accurate for the evaluation of systolic function in patients with CAD. Nonetheless, the evaluation of global LV function by means of MPI may represent a valuable and affordable alternative to expensive and time-consuming methods, especially in the presence of difficult technical settings.
Daniele Pontillo; Nicolino Patruno; Aldo Capezzuto; Francesco Serra; Massimo Sassara; Enrico Vittorio Scabbia
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Angiology     Volume:  53     ISSN:  0003-3197     ISO Abbreviation:  Angiology     Publication Date:    2002 Nov-Dec
Date Detail:
Created Date:  2002-12-04     Completed Date:  2002-12-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  693-8     Citation Subset:  IM    
Division of Cardiology, Belcolle Hospital, Viterbo, Italy.
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MeSH Terms
Coronary Angiography*
Coronary Disease / physiopathology*
Echocardiography, Doppler*
Heart Catheterization
Linear Models
Middle Aged
Stroke Volume / physiology
Ventricular Function, Left / physiology*

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