Document Detail

Comparison of two contrast materials with different iodine concentrations in enhancing the density of the the aorta, portal vein and liver at multi-detector row CT: a randomized study.
MedLine Citation:
PMID:  15309493     Owner:  NLM     Status:  MEDLINE    
This work investigates differences in contrast enhancement of the aorta, portal vein and liver by two different concentrations of contrast materials using an automatic bolus tracking technique. Seventy patients were assigned randomly into one of two groups. Contrast materials with iodine concentrations of 300 and 370 mg/ml were administered to patients in groups A and B, respectively. The total iodine load (600 mg/kg) and injection time (30 s) were identical. Differences in the increase of the Hounsfield unit of the aorta, portal vein and liver between the two groups were examined by t-test. There were no significant differences between the two groups in any of the contrast enhancements of the aorta, portal vein and liver parenchyma at all phases, except for enhancement of the portal vein at the late arterial phase. Females showed better contrast enhancement of the aorta and portal vein than males. With the same iodine dose and injection time, the concentration of contrast materials did not seem to influence the efficacy of contrast enhancement of the aorta, portal vein and liver, except for the portal vein at the late arterial phase. Planning of protocols for contrast media injection may be made irrespective of the iodine concentrations.
Hiromasa Suzuki; Hidekazu Oshima; Norio Shiraki; Chisa Ikeya; Yuta Shibamoto
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2004-08-12
Journal Detail:
Title:  European radiology     Volume:  14     ISSN:  0938-7994     ISO Abbreviation:  Eur Radiol     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-10-25     Completed Date:  2005-03-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  2099-104     Citation Subset:  IM    
Department of Radiology, Nagoya City University Medical School, 1 Kawasumi, Mizuho-cho, Mizuho-ku, 467-8601 Nagoya, Japan.
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MeSH Terms
Aged, 80 and over
Aortography / methods*
Contrast Media / administration & dosage*
Injections, Intravenous
Iohexol / administration & dosage
Iopamidol / administration & dosage
Liver / blood supply,  radiography*
Middle Aged
Portal Vein / radiography*
Radiographic Image Enhancement / methods*
Sex Factors
Tomography, X-Ray Computed / methods*
Reg. No./Substance:
0/Contrast Media; 62883-00-5/Iopamidol; 66108-95-0/Iohexol; 7553-56-2/Iodine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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