| Comparison of two commercial immunoassays for the detection of anti-rubella IgM and IgG in pediatric patients. | |
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MedLine Citation:
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PMID: 17613675 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The only threatening modality of rubella is the Congenital Rubella Syndrome that affects fetuses of women who acquire infection during early pregnancy. Laboratory diagnosis is based on serological parameters. We compared anti-rubella IgM and IgG detection of two commercial immunoassay kits (Abbott and Roche). Although we observed an agreement of 97.8% for IgM and 95.7% for IgG when the categories positive, negative and indeterminate were considered, mean titers of IgG and the absorbance/cut off of IgM were statistically different for both kits, thus corroborating the idea that serological results depend very much on the methodology and must be carefully interpreted. |
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Authors:
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L C Oliveira; T S Okay; K H Kawasato; L P Lima |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of immunoassay & immunochemistry Volume: 28 ISSN: 1532-1819 ISO Abbreviation: J Immunoassay Immunochem Publication Date: 2007 |
Date Detail:
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Created Date: 2007-07-06 Completed Date: 2007-09-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100963688 Medline TA: J Immunoassay Immunochem Country: United States |
Other Details:
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Languages: eng Pagination: 297-306 Citation Subset: IM |
Affiliation:
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Laboratory of Medical Investigation (LIM-36), Department of Pediatrics, School of Medicine, University of São Paulo, Brazil. leaco@icr.hcnet.usp.br |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Antibodies, Viral / analysis, blood* Child Child, Preschool Humans Immunoassay / methods* Immunoglobulin G / analysis, blood* Immunoglobulin M / analysis, blood* Reagent Kits, Diagnostic* Rubella / blood, diagnosis*, immunology |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Viral; 0/Immunoglobulin G; 0/Immunoglobulin M; 0/Reagent Kits, Diagnostic |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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